Evidence map›Paper›PMID 40677365›Full record

ArticleKidney international reports2025

Impact of CKD on Female Reproductive Hormones.

Mahua Bhaduri, Ippokratis Sarris, Pirro Hysi, Kypros Nicolaides, Freya Baird, Kate Bramham

Abstract read
In one paragraph

Article in Kidney international reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mahua BhaduriKing's Fertility, King's College Hospital, The Fetal Medicine Foundation, London, UK.
Ippokratis SarrisKing's Fertility, King's College Hospital, The Fetal Medicine Foundation, London, UK.
Pirro HysiSchool of Life Course and Population Sciences, King's College London, London, UK.
Kypros NicolaidesThe Fetal Medicine Research Institute, King's College Hospital, London, UK.
Freya BairdKing's Fertility, King's College Hospital, The Fetal Medicine Foundation, London, UK.
Kate BramhamSchool of Life Course and Population Sciences, King's College London, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Increasing numbers of women with chronic kidney disease (CKD) are using assisted reproductive technology (ART) to conceive, though the mechanisms by which CKD reduces fertility remain unclear. Methods: This study investigated the impact of CKD on female reproductive hormones through an observational cohort study of 100 women with CKD and 57 healthy controls recruited from 4 hospital sites. Clinical data and serum levels of follicle stimulating hormone (FSH), luteinizing hormone (LH), prolactin, testosterone, estradiol, progesterone, anti-Mullerian hormone (AMH), and β-human chorionic gonadotrophin (β-HCG) were measured during the early menstrual cycle or at convenience for amenorrheic participants. Fertility ultrasounds were also performed, and ethical approval was obtained with participant consent. Results: Compared with healthy controls, patients with CKD had a higher proportion of non-White ethnicity (49.0% vs. 31.8%, Conclusion: This largest prospective study to date on fertility hormonal profiles in CKD underscores the need for longitudinal research to guide informed, timely fertility decisions for women with CKD.

Indexed as

AMHCKDfemale sex hormonesfertilityreproductive hormones

Identifiers

PMID40677365
PMCPMC12266261

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.