Evidence map›Paper›PMID 40677922›Full record

ArticleHuman mutation2025

Identification and Functional Characterization of a Novel PRPS1 Variant in X-Linked Nonsyndromic Hearing Loss: Insights From Zebrafish and Cellular Models.

Yining Wan, Jinqiu Li, Yingyuan Guo, Fang Guo, Ying Zhao, Yue Li, Xia Yang, Huidan Chen, Shimin Xie, Mingyong Wang and 3 more

Abstract read
In one paragraph

Article in Human mutation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yining WanDepartment of Otolaryngology, The Second Hospital of Jilin University, Changchun, Jilin, China.ORCID 0009-0000-1157-2440
Jinqiu LiDepartment of Otolaryngology, The Second Hospital of Jilin University, Changchun, Jilin, China.ORCID 0009-0002-1576-5818
Yingyuan GuoDepartment of Otolaryngology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Fang GuoDepartment of Otolaryngology, The Second Hospital of Jilin University, Changchun, Jilin, China.ORCID 0009-0004-9595-2190
Ying ZhaoDepartment of Otolaryngology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Yue LiAcademicians Workstation of Jilin Province, Changchun University of Chinese Medicine, Changchun, Jilin, China.ORCID 0000-0003-3874-5879
Xia YangAcademicians Workstation of Jilin Province, Changchun University of Chinese Medicine, Changchun, Jilin, China.ORCID 0000-0002-8724-4897
Huidan ChenAcademicians Workstation of Jilin Province, Changchun University of Chinese Medicine, Changchun, Jilin, China.ORCID 0009-0003-3839-7904
Shimin XieAcademicians Workstation of Jilin Province, Changchun University of Chinese Medicine, Changchun, Jilin, China.
Mingyong WangMurui Biological Technology Co. Ltd., Suzhou Industrial Park, Suzhou, Jiangsu, China.ORCID 0000-0002-5705-8145
Guofang GuanDepartment of Otolaryngology, The Second Hospital of Jilin University, Changchun, Jilin, China.ORCID 0000-0003-0633-0441
Yilong ZhuAcademicians Workstation of Jilin Province, Changchun University of Chinese Medicine, Changchun, Jilin, China.ORCID 0000-0003-3924-9324
Xiao LiChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, Jilin, China.ORCID 0009-0005-9367-1202

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DeafnessGenetic Diseases, X-LinkedZebrafish ProteinsAnimalsAnimals, Genetically ModifiedDisease Models, AnimalExome SequencingFemaleHair Cells, AuditoryHumansMaleMitochondriaMutation, MissensePedigreeReactive Oxygen SpeciesSuperoxide DismutaseReactive Oxygen SpeciesSuperoxide DismutaseZebrafish Proteinsexome sequencingnovel variantoxidative stressPRPS1X-linked nonsyndromic hearing loss

Identifiers

PMID40677922
PMCPMC12267977

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.