Evidence map›Paper›PMID 40678338›Full record

ArticleFood science & nutrition2025

The Association Between Weight-Adjusted-Waist Index and S-Klotho Levels in Adults: NHANES 2007-2016.

Jingjing Chen, Qingyi Zeng, Li Liu, Yilan Li, Anning Wang, Yingqi Yi, Zhanglan Wang, Weihong Sun, Wei Zhou, Yun Ye and 1 more

Abstract read
In one paragraph

Article in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jingjing ChenDepartment of Cardiovascular Medicine Affiliated Hospital of Guizhou Medical University Guiyang China.
Qingyi ZengDepartment of Cardiovascular Medicine Affiliated Hospital of Guizhou Medical University Guiyang China.ORCID https://orcid.org/0009-0005-5880-4719
Li LiuDepartment of Cardiovascular Medicine Affiliated Hospital of Guizhou Medical University Guiyang China.
Yilan LiDepartment of Cardiovascular Medicine Affiliated Hospital of Guizhou Medical University Guiyang China.
Anning WangDepartment of Cardiovascular Medicine Affiliated Hospital of Guizhou Medical University Guiyang China.
Yingqi YiDepartment of Cardiovascular Medicine Affiliated Hospital of Guizhou Medical University Guiyang China.
Zhanglan WangDepartment of Cardiovascular Medicine Affiliated Hospital of Guizhou Medical University Guiyang China.
Weihong SunDepartment of Cardiovascular Medicine Affiliated Hospital of Guizhou Medical University Guiyang China.
Wei ZhouDepartment of Cardiovascular Medicine Affiliated Hospital of Guizhou Medical University Guiyang China.
Yun YeDepartment of Cardiovascular Medicine Guizhou Provincial People's Hospital Guiyang China.
Wei LiDepartment of Cardiovascular Medicine Affiliated Hospital of Guizhou Medical University Guiyang China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The weight-adjusted waist index (WWI) is a new obesity metric that may better reflect body fat distribution than traditional measures like body mass index (BMI). However, the link between WWI and serum Klotho levels, an aging biomarker, is not well understood. The study involved non-pregnant adults aged 40 to 79 years who had comprehensive data regarding BMI, waist circumference (WC), and serum Klotho levels. We analyzed data from 12,809 participants aged 40 to 79 years from NHANES. WWI was calculated by dividing WC by the square root of body weight. Participants were categorized into quartiles based on WWI values. A multivariate linear regression model assessed the relationship between WWI and serum Klotho levels, with subgroup analyses for demographic consistency. The analysis showed a significant negative correlation between WWI and serum Klotho levels (

Indexed as

National Health and Nutrition Examination Survey (NHANES)Serum Klotho levelsweight‐adjusted waist index (WWI)

Identifiers

PMID40678338
PMCPMC12268791

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.