Evidence map›Paper›PMID 40679589›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2026

Cerium oxide nanoparticles attenuate hepatic failure via blocking TGF-β/Smads and upregulating Nrf2/HO-1 signaling pathways in liver fibrosis rat model.

Noha A Mowaad, Sara M Baraka, Saber Ibrahim, Doaa A Mansour, Reda M S Korany, Ahmed F El-Sayed, Arwa A Hassan

Abstract read
In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Biomaterial-based therapeutic strategies for oral submucous fibrosis.Frontiers in cell and developmental biology · 2026
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Noha A MowaadNarcotics, Ergogenics and Poisons Department, National Research Centre, Giza, 12622, Egypt.
Sara M BarakaChemistry of Natural Compounds Department, National Research Centre, Giza, 12622, Egypt. sm.baraka@nrc.sci.eg.ORCID 0000-0002-3714-2120
Saber IbrahimPackaging Materials Department, National Research Centre, Giza, 12622, Egypt.
Doaa A MansourDepartment of Biochemistry and Chemistry of Nutrition, Faculty of Veterinary Medicine, University of Sadat City, P.O. Box 32897, Sadat City, Menoufia, Egypt.
Reda M S KoranyPathology Department, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
Ahmed F El-SayedMicrobial Genetics Department, Biotechnology Research Institute, National Research Centre, Giza, 12622, Egypt.
Arwa A HassanPharmacology and Toxicology, Ministry of Health & Population, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

T his article is aimed at assessing the anti-fibrotic action of plant-based fabricated cerium oxide nanoparticles (CeO

Indexed as

CeriumLiver CirrhosisMetal NanoparticlesNanoparticlesAnimalsHeme Oxygenase-1Heme Oxygenase (Decyclizing)LiverMaleNF-E2-Related Factor 2Oxidative StressPlant ExtractsRatsRats, Sprague-DawleySignal TransductionSmad Proteinsceric oxideCeriumHeme Oxygenase-1Heme Oxygenase (Decyclizing)Hmox1 protein, ratNfe2l2 protein, ratNF-E2-Related Factor 2Plant ExtractsSmad ProteinsThioacetamideTransforming Growth Factor betaTransforming Growth Factor beta1CeO2 nanoparticlesGreen synthesisIn silicoLiver fibrosisNrf2TGF-β/Smads

Identifiers

PMID40679589
PMCPMC12894128

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.