ArticleEndocrine2025
Correlation between postoperative serum bone metabolism levels and fracture healing in elderly osteoporotic fracture patients.
Article in Endocrine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Effect of fibular rotation and sagittal shift on postoperative function in ankle fractures with syndesmotic injury.American journal of translational research · 2026Article
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Authors and funding
2 authors.
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Abstract
purposeTo investigate the correlation between postoperative serum bone metabolism levels and fracture healing in elderly patients with osteoporotic vertebral compression fractures (OVCFs).
methods110 OVCF patients treated in the hospital from February 2023 to January 2024 were enrolled in this study. The patients were divided into the Normal healing and Delayed healing groups based on postoperative fracture healing. The general information of the two groups was first compared, and then serum levels of procollagen type I N-terminal propeptide (P1NP), osteoprotegerin (OPG), osteocalcin (BGP), and alkaline phosphatase (ALP) were measured in the patients. The correlation between postoperative bone metabolism levels and bone mineral density (BMD) and postoperative Oswestry disability index (ODI) were analyzed using Spearman's correlation test. Independent risk factors affecting postoperative fracture healing time were analyzed using multifactorial logistic regression. The value of serum bone metabolism indexes in assessing delayed postoperative fracture healing was analyzed using the receiver operating characteristic (ROC) curves.
resultsIn the Delayed healing group, the age, proportion of comorbid diabetes mellitus, postoperative ODI, and fracture healing time were significantly higher than those in the Normal healing group. Conversely, the postoperative calcium-phosphorus product, 25-hydroxyvitamin D [25(OH)D
conclusionsDelayed postoperative fracture healing in elderly OVCF patients might be affected by serum P1NP, OPG, BGP, and ALP levels, and serum bone metabolism levels can be an auxiliary judgment indicator of delayed postoperative fracture healing.
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