Evidence map›Paper›PMID 40681262›Full record

ArticleJACC. Case reports2025

A Tale of Two Zebras: Cardiac Intimal Sarcoma Discovered in a Male Patient With SCAD and ADPKD.

Jay A Patel, Matthew G Kaye, Aditya Kesari, Arun U Mahtani, Jonathan Kanakaraj, Adam Dossaji, Barbara D Lawson, Mohammed A Quader, Patricia Nicolato, Keyur B Shah

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jay A PatelDivision of Cardiothoracic Surgery, Department of Surgery, Virginia Commonwealth University Medical Center, Richmond, Virginia, USA.
Matthew G KayeDivision of Cardiology, Department of Internal Medicine, Virginia Commonwealth University Medical Center, Richmond, Virginia, USA. Electronic address: matthew.kaye@vcuhealth.org.
Aditya KesariDivision of General Internal Medicine, Department of Medicine, Virginia Commonwealth University Medical Center, Richmond, Virginia, USA.
Arun U MahtaniDivision of Cardiology, Department of Internal Medicine, Virginia Commonwealth University Medical Center, Richmond, Virginia, USA.
Jonathan KanakarajDepartment of Pathology, Virginia Commonwealth University Medical Center, Richmond, Virginia, USA.
Adam DossajiDivision of Nephrology, Department of Internal Medicine, Virginia Commonwealth University Medical Center, Richmond, Virginia, USA.
Barbara D LawsonDivision of Cardiology, Department of Internal Medicine, Virginia Commonwealth University Medical Center, Richmond, Virginia, USA.
Mohammed A QuaderDivision of Cardiothoracic Surgery, Department of Surgery, Virginia Commonwealth University Medical Center, Richmond, Virginia, USA.
Patricia NicolatoDivision of Cardiothoracic Surgery, Department of Surgery, Virginia Commonwealth University Medical Center, Richmond, Virginia, USA.
Keyur B ShahDivision of Cardiology, Department of Internal Medicine, Virginia Commonwealth University Medical Center, Richmond, Virginia, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiac intimal sarcoma is a very rare vascular-based sarcoma that arises from the left atrium and pulmonary artery. CASE SUMMARY: A 58-year-old male with a history of coronary artery disease, prior coronary artery bypass grafting, and spontaneous coronary artery dissection (SCAD) presented with myocardial infarction and was referred for heart transplantation. Further investigation revealed previously undiagnosed autosomal dominant polycystic kidney disease (ADPKD). During cardiac explantation, an incidental high-grade cardiac intimal sarcoma was discovered. DISCUSSION: In male patients, SCAD and cardiac intimal sarcomas are both rare entities. Although ADPKD is associated with SCAD and solid tumor malignancies, its potential association with cardiac sarcoma is not well defined. TAKE-HOME MESSAGES: This case highlights the importance of investigating secondary causes of SCAD, particularly when it presents in a male patient. Additionally, this case suggests a potential connection between ADPKD and cardiac intimal sarcoma.

Indexed as

acute coronary syndromeacute heart failurecancercardiac transplantation

Identifiers

PMID40681262
PMCPMC12441359

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.