Evidence map›Paper›PMID 40682007›Full record

ArticleBMC nephrology2025

Experimental study of intravoxel incoherent motion diffusion imaging combined with ultrasound renal resistance index in contrast-induced nephropathy.

Jinlong Chen, Xiaoyu Song, Zhao Wang, Zhiqiang Wang

Abstract read
In one paragraph

Article in BMC nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jinlong ChenCollege of Clinical Medicine, Beihua University, Jilin, China.
Xiaoyu SongCollege of Clinical Medicine, Beihua University, Jilin, China.
Zhao WangDepartment of Ultrasound, Siping Central People's Hospital, Siping, China.
Zhiqiang WangDepartment of Radiology, The Affiliated Hospital of BeiHua University, Jilin, China. beihuawangzhiqiang@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study explored the application of Intravoxel Incoherent Motion (IVIM) diffusion imaging combined with Ultrasound Renal Resistance Index (RRI) for monitoring the pathophysiological changes associated with early contrast-induced nephropathy (CIN).

methodsIn this study, forty-two male Sprague-Dawley (SD) rats were equally divided into two groups: a contrast media (CM) group and a control group, each containing 21 animals. The CM group was administered a tail vein injection of ioversol (370 mg I/ml, 1.5 ml/kg), while the control group received a saline solution in a similar volume. Assessments using IVIM-MRI and Doppler ultrasound were performed 24 h before and at 1, 24, 48, and 72 h post-injection. These assessments aimed to evaluate the true diffusion coefficient (D), pseudo-diffusion coefficient (D

resultsPost-ioversol administration, significant declines were noted in the D, D

conclusionThe synergistic application of IVIM and RRI techniques offers a non-invasive approach for early detection of renal damage after ioversol exposure and is a potent method for observing the pathophysiological shifts associated with early-stage CIN.

Indexed as

Contrast MediaDiffusion Magnetic Resonance ImagingKidneyKidney DiseasesTriiodobenzoic AcidsAnimalsHypoxia-Inducible Factor 1, alpha SubunitMaleRatsRats, Sprague-DawleyUltrasonography, DopplerContrast MediaHypoxia-Inducible Factor 1, alpha SubunitTriiodobenzoic AcidsAcute kidney injuryContrast-induced nephropathyIntravoxel incoherent motionRenal resistance index

Identifiers

PMID40682007
PMCPMC12273328

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.