ArticleBMC cardiovascular disorders2025
Association between calcium intake and risk of congestive heart failure: a cross-sectional study from the 2003-2018 NHANES database.
Article in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundCongestive heart failure (CHF) is a critical condition resulting from impaired blood pumping, leading to fluid accumulation. While calcium plays a vital role in skeletal health and muscle contraction, its potential in preventing CHF remains unclear.
objectivesThis study aimed to investigate the relationship between calcium intake and the risk of CHF using data from the National Health and Nutrition Examination Survey (NHANES) collected between 2003 and 2018.
methodsAfter completing the questionnaire, participants were classified into CHF and control groups, with calcium intake considered as the primary exposure variable, alongside categorical factors such as age and race. Statistical analyses included t-tests and chi-square tests. A subsequent risk stratification analysis assessed the impact of various covariates on CHF. Additionally, Least Absolute Shrinkage and Selection Operator (LASSO) regression was applied to identify optimal predictor variables, and model performance was evaluated using the receiver operating characteristic curve.
resultsA total of 3,083 participants were included in the study. Baseline characteristics revealed significant differences in race (p = 0.004), education (p = 0.019), fasting glucose (p = 0.047), and calcium intake (p = 0.020) between the CHF and control groups. In model 3, calcium intake was significantly associated with a reduced risk of CHF (p < 0.001, OR = 6.37 × 10
conclusionCalcium intake serves as a protective factor against CHF, potentially lowering its risk. These findings provide theoretical support for the prevention and diagnosis of CHF.
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