Evidence map›Paper›PMID 40682637›Full record

SynthesisOdontology2026

The impact of the number of remaining teeth on the risk of frailty: a meta-analysis.

Akio Tada, Hiroko Miura

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Odontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Akio TadaDepartment of Health Science, Hyogo University, Kakogawa, Hyogo, Japan. atada@hyogo-dai.ac.jp.ORCID http://orcid.org/0000-0002-0844-244X
Hiroko MiuraDivision of Disease Control and Epidemiology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Frailty is commonly linked to a range of factors, and recent reports have highlighted its connection to the number of teeth. The goal of this study was to systematically review and quantitatively assess the current evidence on the connection between the number of remaining teeth and frailty in older adults. By employing a comprehensive search strategy, we identified relevant publications from the past 15 years in the following three electronic databases: PubMed, CINAHL, and Scopus. We followed the PRISMA-P guideline to a systematic review and meta-analysis. We assessed the quality of the studies using the Newcastle-Ottawa Scale and the Grading of Recommendations, Assessment, Development, and Evaluation framework. The inclusion criteria were met by eight studies (six cross-sectional and two cohort studies). Older adults with ≤ 20 teeth had a significantly higher risk of frailty than those with > 20 teeth (odds ratio [OR] = 2.57, 95% confidence interval [CI]: 1.91-3.47). Being edentulous presented higher risk of frailty than being dentate (OR = 1.69 (95% CI 1.32-2.15)). Sensitivity analyses yielded consistent results. According to this meta-analysis and systematic review, tooth loss is considered a potential marker of frailty. Further studies are needed to establish the causality of this relationship.

Indexed as

Frail ElderlyFrailtyTooth LossAgedHumansRisk FactorsFrailtyOlder adultsRemaining teethTooth loss

Identifiers

PMID40682637

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.