ArticleMolecular biotechnology2026
Significance of a Novel Angiogenesis-Related Biomarker Neuropilin-1 in Keloids.
Article in Molecular biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Plant Exosome Injection: A New Boost for Postlaser Vascular Repair.The Journal of clinical and aesthetic dermatology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Keloids are a severe type of pathological scars caused by excessive connective tissue hyperplasia after skin injury. Uncontrolled angiogenesis during wound healing can contribute to keloid formation, highlighting the importance of angiogenesis regulation in keloid prevention and treatment. In this study, angiogenesis-related biomarkers in keloids were identified using a combination of machine learning methods and weighted gene co-expression network analysis (WGCNA), based on gene expression data from the Gene Expression Omnibus (GEO) database. Neuropilin-1 (NRP1) was selected for further investigation and validated in clinical tissue samples using immunohistochemistry (IHC) and quantitative reverse transcription polymerase chain reaction (RT-qPCR). Immune microenvironment analysis indicated a significant positive correlation between the NRP1 expression level and the abundance of immune and stromal cells, particularly endothelial cells. The biological role of NRP1 at the single-cell level revealed that keloid endothelial cells potentially promote collagen deposition in the extracellular matrix (ECM), which is closely associated with the keloid NRP1
Indexed as
Identifiers
40684009What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.