ArticleAnimal microbiome2025
Direct-fed microbials optimize ruminal fermentation, microbial ecosystem and milk quality to enhance the lactation performance of Sanhe dairy cows.
Article in Animal microbiome, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Effects of compound Chinese herbal microecological preparations on growth performance, meat quality and rumen microflora of Simmental cattle.Frontiers in genetics · 2026Article
- Effect of direct-fed microbial feed blocks on blood β-hydroxybutyrate and milk yield in early postpartum buffaloes under field conditions.Veterinary world · 2026Article
- Effects of Partial Replacement of Alfalfa Hay with Alfalfa Silage in Dairy Cows: Impacts on Production Performance and Rumen Microbiota.Animals : an open access journal from MDPI · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
The growing global population and rising living standards require a higher supply of dairy products. Dairy cows are the most important source of milk production, with billions of microorganisms present in the rumen. This study aims to assess the impact of direct-fed microbials (DFMs) containing Lentilactobacillus buchneri, Bifidobacterium longum, and Pediococcus pentosaceus on rumen fermentation parameters, rumen microbial composition, and lactation performance in dairy cows. Twelve Sanhe dairy cows with similar physical condition, parity and lactation were randomly divided into two groups of six cows each. The control group was fed a basal diet and the treatment group was fed a basal diet plus DFMs (20 g/day) for the experimental period of 60 days. Rumen fluid, blood, milk, and feces were collected from cows for detection and analysis. DFMs enhanced the apparent total tract digestibility of crude protein and neutral detergent fiber (P < 0.05), and elevated milk protein rate of Sanhe dairy cows (P < 0.05). In the ruminal environment, supplementation of DFMs promoted the production of microbial proteins, acetate and total volatile fatty acids (P < 0.05). High-throughput sequencing analysis of rumen microorganisms revealed that relative abundance of DFMs were elevated in the treatment group, and DFMs enhanced the relative abundance of Prevotella, Pseudoclostridium and Faecalibacterium in the rumen (P < 0.05). In predictive analysis of microbial functional genes, the treatment group was enriched with more genes encoding hemicellulose-degrading enzymes such as GH10, GH30, and GH67, while the relative abundance of genes encoding enzymes that metabolize ammonia was increased. In addition, the analysis of rumen bacteriophages showed that DFMs significantly increased the relative abundance of bacteriophages infecting Prevotella in the rumen. Overall, DFMs enhanced the degradation of protein and carbohydrate in Sanhe dairy cows. There was a positive correlation with the relative abundance of Prevotella, which may provide substant amino acids and energy for milk protein synthesis, improving the lactation performance of Sanhe dairy cows.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.