Evidence map›Paper›PMID 40685803›Full record

ArticlePhysiological reports2025

Impact of aging on cardiovascular dynamics and heart rate variability during passive head-up tilt.

Manoj Kumar Choudhary, Kati Holmström, Heidi Bouquin, Tuomas P Saarinen, Jenni K Koskela, Essi Pietilä, Lauri Suojanen, Jukka T Mustonen, Pasi I Nevalainen, Ilkka H Pörsti

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiological reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Manoj Kumar ChoudharyFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.ORCID 0000-0002-6722-6384
Kati HolmströmFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Heidi BouquinFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Tuomas P SaarinenFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Jenni K KoskelaFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Essi PietiläFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Lauri SuojanenFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Jukka T MustonenFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Pasi I NevalainenDepartment of Internal Medicine, Tampere University Hospital, Tampere, Finland.
Ilkka H PörstiFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.ORCID 0000-0002-4905-7564

Funding

Aarne Koskelon Säätiö (Aarne Koskelo Foundation)Päivikki ja Sakari Sohlbergin Säätiö (Päivikki and Sakari Sohlberg Foundation)Sigrid Juséliuksen Säätiö (Sigrid Jusélius Stiftelse)SKR | Pirkanmaan Rahasto (Pirkanmaa Regional Fund) 50241469Suomen Lääketieteen Säätiö (Finnish Medical Foundation) 7613Sydäntutkimussäätiö (Finnish Foundation for Cardiovascular Research) 240009Tampereen Tuberkuloosisäätiö (Tampere Tuberculosis Foundation)Tays (Tampere University Hospital) 9AB057Tays (Tampere University Hospital) 9AC076
6 · The paper itself

Abstract

During aging, arterial stiffness and blood pressure (BP) increase, while heart rate variability (HRV) decreases. We examined age-related hemodynamics in 522 individuals without cardiovascular disease during passive head-up tilt (HUT) using pulse wave analysis, whole-body impedance cardiography, and HRV analysis. Mean age was 44 years, body mass index 26 kg/m

Indexed as

AgingHeart RateHemodynamicsAdultAgedBlood PressureFemaleHumansMaleMiddle AgedPulse Wave AnalysisTilt-Table TestVascular ResistanceVascular Stiffnessagingblood pressurehead‐up tiltheart ratehemodynamics

Identifiers

PMID40685803
PMCPMC12277527

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.