Evidence map›Paper›PMID 40686922›Full record

ArticleMedComm2025

Association Between Preoperative Cognitive Performance and Postoperative Delirium in Older Patients: Results From a Multicenter, Prospective Cohort Study, and a Mendelian Randomization Study.

Rao Sun, Shiyong Li, Changming Yang, Guiming Huang, Chunrong Tang, Wei Li, Zhongyuan Xia, Mingzhang Zuo, Ning Yang, Huiyu Luo and 15 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in MedComm, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Rao SunDepartment of Anesthesiology and Pain Medicine, Hubei Key Laboratory of Geriatric Anesthesia and Perioperative Brain Health, and Wuhan Clinical Research Center for Geriatric Anesthesia Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan China.
Shiyong LiDepartment of Anesthesiology and Pain Medicine, Hubei Key Laboratory of Geriatric Anesthesia and Perioperative Brain Health, and Wuhan Clinical Research Center for Geriatric Anesthesia Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan China.
Changming YangDepartment of Anesthesiology Jingmen Central Hospital Jingmen China.
Guiming HuangDepartment of Anesthesiology Ganzhou People's Hospital Ganzhou China.
Chunrong TangDepartment of Anesthesiology Songzi People's Hospital Jingzhou China.
Wei LiDepartment of Anesthesiology Gong'an County People's Hospital Jingzhou China.
Zhongyuan XiaDepartment of Anesthesiology Renmin Hospital of Wuhan University Wuhan China.
Mingzhang ZuoDepartment of Anesthesiology Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences Beijing China.
Ning YangDepartment of Anesthesiology Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences Beijing China.
Huiyu LuoDepartment of Anesthesiology No.1 People's Hospital Hubei University of Medicine Xiangyang China.
Kun ZhangDepartment of Anesthesiology Jingzhou Hospital Affiliated to Yangtze University Jingzhou China.
Huajun LiDepartment of Anesthesiology Jianshi County People's Hospital Enshi China.
Qingfeng ZengDepartment of Anesthesiology Gong'an County Traditional Chinese Medicine Hospital Jingzhou China.
Chun ChenDepartment of Anesthesiology Yichang Central People's Hospital, The First College of Clinical Medical Science, China Three Gorges University Yichang China.
Lan WangDepartment of Anesthesiology Jingzhou Third People's Hospital Jingzhou China.
Rui XiaDepartment of Anesthesiology The First Affiliated Hospital of Yangtze University Jingzhou China.
Chuanbin DongDepartment of Anesthesiology Zhijiang People's Hospital Yichang China.
Junmin HeDepartment of Anesthesiology Jingmen People's Hospital Jingmen China.
Qiaoqiao XuDepartment of Anesthesiology and Pain Medicine, Hubei Key Laboratory of Geriatric Anesthesia and Perioperative Brain Health, and Wuhan Clinical Research Center for Geriatric Anesthesia Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan China.
Xinhua LiDepartment of Anesthesiology and Pain Medicine, Hubei Key Laboratory of Geriatric Anesthesia and Perioperative Brain Health, and Wuhan Clinical Research Center for Geriatric Anesthesia Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan China.
Biyun ZhouDepartment of Anesthesiology and Pain Medicine, Hubei Key Laboratory of Geriatric Anesthesia and Perioperative Brain Health, and Wuhan Clinical Research Center for Geriatric Anesthesia Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan China.
Shangkun LiuDepartment of Anesthesiology and Pain Medicine, Hubei Key Laboratory of Geriatric Anesthesia and Perioperative Brain Health, and Wuhan Clinical Research Center for Geriatric Anesthesia Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan China.
Fang LuoDepartment of Anesthesiology and Pain Medicine, Hubei Key Laboratory of Geriatric Anesthesia and Perioperative Brain Health, and Wuhan Clinical Research Center for Geriatric Anesthesia Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan China.
Zhiqiang ZhouDepartment of Anesthesiology and Pain Medicine, Hubei Key Laboratory of Geriatric Anesthesia and Perioperative Brain Health, and Wuhan Clinical Research Center for Geriatric Anesthesia Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan China.
Ailin LuoDepartment of Anesthesiology and Pain Medicine, Hubei Key Laboratory of Geriatric Anesthesia and Perioperative Brain Health, and Wuhan Clinical Research Center for Geriatric Anesthesia Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated the association between preoperative cognitive performance and postoperative delirium (POD) using a multicenter prospective cohort, and explored potential causality using Mendelian randomization (MR) analysis. We analyzed data from 2257 patients aged ≥ 75 years undergoing elective noncardiac and noncranial surgeries across 16 Chinese medical centers. Preoperative cognitive assessment using Mini-Cog revealed 28.4% of patients had cognitive impairment (score ≤ 2). POD occurred in 9.7% of patients, with higher incidence among those with cognitive impairment. Logistic regression demonstrated that cognitive impairment was significantly associated with increased POD risk (odds ratio [OR], 2.06; 95% confidence interval [CI], 1.55-2.74;

Indexed as

cognitive impairmentMendelian randomizationMini‐Cog testpostoperative deliriumprospective cohort study

Identifiers

PMID40686922
PMCPMC12271639

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.