ArticlePreventive medicine reports2025
Association between hemoglobin-to-red blood cell distribution width ratio and rheumatoid arthritis in US adults: evidence from the national health and nutrition examination survey 2009-2018.
Article in Preventive medicine reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This cross-sectional study aimed to investigate the association between the hemoglobin-to-red blood cell distribution width ratio (HRR) and rheumatoid arthritis in adults. Methods: Cross-sectional data from 22,352 participants in the National Health and Nutrition Examination Survey (NHANES) 2009-2018 were analyzed. HRR was defined as hemoglobin concentration (g/dL) divided by red blood cell distribution width (%) and grouped into quartiles. The multivariable logistic regression model and restricted cubic spline (RCS) models assessed the connection between HRR and rheumatoid arthritis, adjusted for demographics, socioeconomic factors, and comorbidities. Results: Our findings reveal a significant negative correlation between HRR measurements and rheumatoid arthritis susceptibility. Higher HRR quartiles showed progressively lower rheumatoid arthritis risk (quartile 4 vs. quartile 1: OR = 0.68, 95 % CI: 0.56,0.83). RCS revealed an inverse linear association after adjustment (P for overall <0.001; P for nonlinear = 0.174). Conclusions: HRR is inversely associated with rheumatoid arthritis risk, suggesting its potential as a biomarker for rheumatoid arthritis risk stratification. Nevertheless, additional investigations are required to corroborate these observations.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.