Evidence map›Paper›PMID 40688018›Full record

ReviewBioactive materials2025

Strategies and applications of antibacterial surface-modified biomaterials.

Qianwei Su, Yunyun Xue, Chuyao Wang, Qirong Zhou, Yu Zhao, Jiacan Su, Baoku Zhu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Bioactive materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qianwei SuDepartment of Polymer Science and Engineering, ERC of Membrane Water Treatment (MOE), Key Laboratory of Macromolecular Synthesis and Functionalization (MOE), Zhejiang University, Hangzhou, 310027, China.
Yunyun XueDepartment of Polymer Science and Engineering, ERC of Membrane Water Treatment (MOE), Key Laboratory of Macromolecular Synthesis and Functionalization (MOE), Zhejiang University, Hangzhou, 310027, China.
Chuyao WangDepartment of Polymer Science and Engineering, ERC of Membrane Water Treatment (MOE), Key Laboratory of Macromolecular Synthesis and Functionalization (MOE), Zhejiang University, Hangzhou, 310027, China.
Qirong ZhouInstitute of Translational Medicine, Shanghai University, Shanghai, 200444, China.
Yu ZhaoDepartment of Polymer Science and Engineering, ERC of Membrane Water Treatment (MOE), Key Laboratory of Macromolecular Synthesis and Functionalization (MOE), Zhejiang University, Hangzhou, 310027, China.
Jiacan SuInstitute of Translational Medicine, Shanghai University, Shanghai, 200444, China.
Baoku ZhuDepartment of Polymer Science and Engineering, ERC of Membrane Water Treatment (MOE), Key Laboratory of Macromolecular Synthesis and Functionalization (MOE), Zhejiang University, Hangzhou, 310027, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial infections and biofilm-associated antibiotic resistance continue to pose significant challenges in biomedical applications, often resulting in device-related complications and therapeutic failures. To address these concerns, the development of antibacterial surface-engineered biomaterials has become a major research focus, offering localized, non-systemic strategies to combat microbial contamination. This review provides a comprehensive overview of recent advances in antibacterial surfaces, with a focus on their mechanisms of action, design principles, and functional performance. Strategies are discussed within the widely recognized categories of active, passive, and hybrid systems. Active surfaces function through agent release or contact-mediated killing, while passive surfaces inhibit bacterial adhesion by modulating surface topography or chemistry. Hybrid systems integrate both mechanisms to achieve synergistic effects. The review also highlights current and emerging applications in medical implants, wound care, and hygienic textiles. Finally, key limitations and future opportunities are critically examined, offering insights into the rational design and clinical translation of next-generation antibacterial biomaterials.

Indexed as

Antibacterial surfacesBacterial infectionBiofilmBiomaterials

Identifiers

PMID40688018
PMCPMC12274879

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.