ArticleJournal of thoracic disease2025
Nutritional status of patients with driver gene mutation-negative non-small cell lung cancer after postoperative adjuvant chemotherapy.
Article in Journal of thoracic disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- The effect of immunonutritional support in patients undergoing surgery and adjuvant chemotherapy for lung cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
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9 authors.
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Abstract
Background: Non-small cell lung cancer (NSCLC) remains a significant challenge for public health and is closely associated with malnutrition; however, few studies have attempted to examine the malnutrition experienced by patients with driver gene-negative NSCLC who have undergone combined chemotherapy after surgery. This study aimed to evaluate the nutritional status of patients with driver gene-negative NSCLC who received adjuvant chemotherapy after surgery and examined the application value of three nutritional screening tools: Nutritional Risk Screening Scale 2022 (NRS-2002), the Prognostic Nutritional Index (PNI), and the Patient-Generated Subjective Global Assessment Scale (PG-SGA). Methods: Data from patients with driver gene-negative NSCLC who underwent sleeve surgery and adjuvant chemotherapy at Shanghai Pulmonary Hospital from January 2021 to December 2021 were prospectively collected. The NRS-2002, PG-SGA, and PNI were used to assess the risk of malnutrition in patients. The correlation between the three nutritional screening tools and various nutritional indicators was analyzed, and the diagnostic efficacy of the three nutritional screening tools was compared using the Global Leadership Initiative on Malnutrition as the gold standard for malnutrition assessment (diagnosis). Results: There was a correlation between the three nutritional screening tools and human body composition and blood biochemical indicators (P<0.05), and the composite correlation coefficient between PNI and various nutritional indicators was the highest (r=0.683; P<0.001). In the evaluation of diagnostic efficacy, PG-SGA demonstrated the highest sensitivity and accuracy index of 85.70% and 54.00%, respectively, while the NRS-2002 had the highest specificity at 71.30%. Conclusions: All three nutritional screening tools can provide a basis for diagnosing malnutrition in patients with driver gene-negative NSCLC after postoperative adjuvant chemotherapy, and their combined application in clinical practice can more comprehensively reflect the nutritional status of these patients.
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