Evidence map›Paper›PMID 40689220›Full record

ArticleInfection and drug resistance2025

Development and Validation of a Nomogram for Predicting Multidrug-Resistant

Zhuman Du, Dan Yang, Linhai Pan, Qianglin Zeng, Xiaoju Chen

Abstract read
In one paragraph

Article in Infection and drug resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhuman DuDepartment of Respiratory and Critical Care Medicine, Clinical Medicine College & Affiliated Hospital of Chengdu University, Chengdu, People's Republic of China.ORCID 0009-0003-9852-7942
Dan YangCenter of Gerontology and Geriatrics, West China Hospital, Sichuan University, Chengdu, People's Republic of China.
Linhai PanDepartment of Respiratory and Critical Care Medicine, Clinical Medicine College & Affiliated Hospital of Chengdu University, Chengdu, People's Republic of China.
Qianglin ZengDepartment of Respiratory and Critical Care Medicine, Clinical Medicine College & Affiliated Hospital of Chengdu University, Chengdu, People's Republic of China.
Xiaoju ChenDepartment of Respiratory and Critical Care Medicine, Clinical Medicine College & Affiliated Hospital of Chengdu University, Chengdu, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The management of multidrug-resistant Methods: This retrospective study collected 3132 bronchoalveolar lavage fluid specimens from a large tertiary comprehensive hospital in southwestern China over a two-year period (20232024). A total of 209 patients with Results: Thirteen predictors were identified: Age, prolonged hospitalization; Cor pulmonale, cardiac insufficiency, old cerebral infarction, chronic renal failure; ventilation, tracheostomy, nasogastric intubation; Cefoperazone-sulbactam, aminoglycosides, antifungals; Hemoglobin levels. The model showed strong predictive accuracy with AUC values of 0.853 (95% CI 0.793-0.914) in training and 0.972 (0.931-1.000) in validation cohorts. Calibration demonstrated excellent consistency (Hosmer-Lemeshow Conclusion: In this study, we developed and validated a predictive model for MDR-PA pneumonia risk by integrating host comorbidities, iatrogenic interventions, and antimicrobial exposure. The model demonstrates potential utility in early identification of high-risk patients and may inform antimicrobial stewardship strategies in regions with predominant cephalosporin/aminoglycoside resistance patterns.

Indexed as

multidrug resistancenomogrampseudomonas aeruginosarisk factor

Identifiers

PMID40689220
PMCPMC12276756

What Socratic holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.