Evidence map›Paper›PMID 40689396›Full record

ArticleMediators of inflammation2025

Orphan Class A GPCRs Signature Predicts Prognosis and Immune Microenvironment in Gastric Cancer: GPR176 Drives Tumor Progression Through Wnt Signaling and Macrophage Polarization.

Jiahui Lin, Lingling Ke, Sha Cheng, Wei Lu, Yanan Hu, Xiyi He, Tingting Luo, Yuting Liu, Canxia Xu, Jian Qi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Mediators of inflammation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jiahui LinDigestive Diseases Center, Guangdong Provincial Key Laboratory of Digestive Cancer Research, The Seventh Affiliated Hospital, Sun Yat-Sen University, Shenzhen, Guangdong 518107, China.ORCID https://orcid.org/0000-0001-5667-5750
Lingling KeDigestive Diseases Center, Guangdong Provincial Key Laboratory of Digestive Cancer Research, The Seventh Affiliated Hospital, Sun Yat-Sen University, Shenzhen, Guangdong 518107, China.ORCID https://orcid.org/0009-0007-2693-5663
Sha ChengDepartment of Gastroenterology, Third Xiangya Hospital of Central South University, Changsha 410013, China.ORCID https://orcid.org/0000-0001-6246-831X
Wei LuDepartment of Gastroenterology, Third Xiangya Hospital of Central South University, Changsha 410013, China.
Yanan HuDepartment of Pediatric Pulmonology and Immunology, West China Second University Hospital, Sichuan University, Chengdu 610041, China.ORCID https://orcid.org/0000-0002-8907-8597
Xiyi HeDepartment of Laboratory Medicine, Baiyun District People's Hospital of Guangzhou, Guangzhou 510000, China.
Tingting LuoDigestive Diseases Center, Guangdong Provincial Key Laboratory of Digestive Cancer Research, The Seventh Affiliated Hospital, Sun Yat-Sen University, Shenzhen, Guangdong 518107, China.ORCID https://orcid.org/0009-0003-0525-8529
Yuting LiuDigestive Diseases Center, Guangdong Provincial Key Laboratory of Digestive Cancer Research, The Seventh Affiliated Hospital, Sun Yat-Sen University, Shenzhen, Guangdong 518107, China.ORCID https://orcid.org/0009-0003-1692-6334
Canxia XuDepartment of Gastroenterology, Third Xiangya Hospital of Central South University, Changsha 410013, China.ORCID https://orcid.org/0000-0002-6166-6653
Jian QiDigestive Diseases Center, Guangdong Provincial Key Laboratory of Digestive Cancer Research, The Seventh Affiliated Hospital, Sun Yat-Sen University, Shenzhen, Guangdong 518107, China.ORCID https://orcid.org/0000-0003-1645-4501

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MacrophagesReceptors, G-Protein-CoupledStomach NeoplasmsWnt Signaling PathwayCell Line, TumorCell MovementCell ProliferationDisease ProgressionFemaleGene Expression Regulation, NeoplasticHumansMaleMiddle AgedPrognosisTumor MicroenvironmentReceptors, G-Protein-Coupledgastric cancerGPR176human orphan class A G protein-coupled receptorsmacrophage polarizationprognostic model

Identifiers

PMID40689396
PMCPMC12274089

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.