Evidence map›Paper›PMID 40689545›Full record

ArticleJournal of the American Heart Association2025

Variant-Specific Late Gadolinium Enhancement Patterns Influence Clinical Outcomes in

Matteo Castrichini, Ramin Garmany, Konstantinos C Siontis, Jeremy D Collins, John P Bois, Naveen L Pereira, David J Tester, Martina Gluscevic, Trung Huynh, Raquel Neves and 3 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Experimental and therapeutic medicine · 2026
    Article
  2. Review
  3. Role of cardiovascular magnetic resonance in diagnosis and management of muscular dystrophies.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Matteo CastrichiniDepartment of Cardiovascular Medicine Mayo Clinic Rochester MN USA.ORCID 0000-0002-2405-3364
Ramin GarmanyMayo Clinic Medical Scientist Training Program Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic Alix School of Medicine Rochester MN USA.ORCID 0000-0002-5756-7417
Konstantinos C SiontisDepartment of Cardiovascular Medicine Mayo Clinic Rochester MN USA.ORCID 0000-0002-6658-0971
Jeremy D CollinsDepartment of Radiology Mayo Clinic Rochester MN USA.ORCID 0000-0003-0707-1736
John P BoisDepartment of Cardiovascular Medicine Mayo Clinic Rochester MN USA.
Naveen L PereiraDepartment of Cardiovascular Medicine Mayo Clinic Rochester MN USA.ORCID 0000-0003-3813-3469
David J TesterDepartment of Molecular Pharmacology and Experimental Therapeutics Mayo Clinic Rochester MN USA.ORCID 0000-0003-4554-2244
Martina GluscevicDepartment of Molecular Pharmacology and Experimental Therapeutics Mayo Clinic Rochester MN USA.
Trung HuynhMayo Clinic Medical Scientist Training Program Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic Alix School of Medicine Rochester MN USA.
Raquel NevesDepartment of Molecular Pharmacology and Experimental Therapeutics Mayo Clinic Rochester MN USA.ORCID 0000-0003-2619-0036
Andrew N RosenbaumDepartment of Cardiovascular Medicine Mayo Clinic Rochester MN USA.ORCID 0000-0001-9202-0233
Michael J AckermanDepartment of Cardiovascular Medicine Mayo Clinic Rochester MN USA.ORCID 0000-0002-8011-3333
John R GiudicessiDepartment of Cardiovascular Medicine Mayo Clinic Rochester MN USA.ORCID 0000-0001-5871-0265

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDisease-causative variants in

methodsRetrospective analysis of 822 genotype-positive patients with arrhythmogenic/dilated cardiomyopathy was used to identify those with disease-causative variants in

resultsAmong the 72/116 (62%)

conclusions

Indexed as

CardiomyopathiesCardiomyopathy, DilatedContrast MediaGadoliniumLamin Type AMagnetic Resonance Imaging, CineAdultAgedDeath, Sudden, CardiacFemaleGenetic Predisposition to DiseaseHumansMaleMiddle AgedRetrospective StudiesContrast MediaGadoliniumLamin Type ALMNA protein, humanarrhythmogenic cardiomyopathygenotype–phenotype correlationlaminopathy

Identifiers

PMID40689545
PMCPMC12449980

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.