ReviewACS biomaterials science & engineering2025
Bacterial-Derived Polyhydroxyalkanoate/Bioceramic Composites in Clinical Practice: State of the Art and Future Perspectives.
Review in ACS biomaterials science & engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- The Role of Polyhydroxyalkanoates in Veterinary Medicine: Biosynthesis, Material Modifications and Clinical Applications.Materials (Basel, Switzerland) · 2026Review
- Polyhydroxyalkanoates in Bone Alloplastic Materials: State of the Art and Future Perspectives.Polymers · 2026Review
- Electron transfer properties of biobased and biodegradable polymers: PHA as a case study.Journal of molecular modeling · 2026Article
- Composite Nanoarchitectonics with Turmeric-Functionalized Layered Double Hydroxide/Poly(3-hydroxyoctanoate) as Bioactive Coatings for Bone and Nerve Regeneration.ACS applied materials & interfaces · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review examines the current advancements in and potential of bioceramic/polyhydroxyalkanoate (BioC/PHA) composites, emphasizing their growing role in biomedical applications. The integration of PHAs─biodegradable, biocompatible polymers from a bacterial origin─with bioceramics like hydroxyapatite or bioglass offers a unique synergy, combining the structural integrity of ceramics with the tunable properties of PHAs. Such composites demonstrate significant promise in bone tissue engineering, cartilage repair, and drug delivery systems, where they support cell attachment, proliferation, and targeted therapeutic release. The review highlights various methods of manufacturing these composites. Additionally, the review addresses challenges in production scalability, cost, and material purification necessary to meet medical-grade standards. Advances in functionalization, such as drug incorporation and bioactive coatings, are discussed as pathways to customized therapeutic solutions. This review underscores the transformative potential of BioC/PHA composites in creating sustainable, multifunctional biomaterials that align with the clinical demands of regenerative medicine and environmentally conscious material science.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.