Evidence map›Paper›PMID 40692528›Full record

ArticleMagnetic resonance in medicine2025

Multi-site feasibility and reproducibility study on UTE 3D phosphorous MRSI using novel rosette trajectory (PETALUTE).

Seyma Alcicek, Alexander R Craven, Xin Shen, Mark Chiew, Ali Ozen, Stephen Sawiak, Ulrich Pilatus, Uzay E Emir

Abstract readMulticenter Study
In one paragraph

Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Feasibility of ConcurrentNMR in biomedicine · 2026
    Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Seyma AlcicekGoethe University Frankfurt, University Hospital, Institute of Neuroradiology, Frankfurt am Main, Germany.ORCID https://orcid.org/0000-0002-9447-4906
Alexander R CravenDepartment of Clinical Engineering, Haukeland University Hospital, Bergen, Norway.
Xin ShenRadiology and biomedical imaging, University of California, San Francisco, California, USA.ORCID https://orcid.org/0000-0003-0184-8751
Mark ChiewPhysical Sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0001-6272-8783
Ali OzenDepartment of Radiology, Medical Physics, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Stephen SawiakDepartment of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
Ulrich PilatusGoethe University Frankfurt, University Hospital, Institute of Neuroradiology, Frankfurt am Main, Germany.
Uzay E EmirWeldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana, USA.ORCID https://orcid.org/0000-0001-5376-0431

Funding

Indiana Clinical and Translational Sciences InstituteUM1TR004402 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI Sharon M Moe, Sarah Elizabeth Wiehe · 2023 to 2026
$21.6M
Else Kröner-Fresenius-Stiftung (EKFS)Indiana Clinical and Translational Sciences InstituteMildred Scheel Career Center (Deutsche Krebshilfe)National Institutes of Health (USA) S10UM1TR004402NCATS NIH HHS UM1 TR004402Wellcome Trust 223131Wellcome Trust 223131/Z/21/Z
6 · The paper itself

Abstract

purposeThis study aims (1) to implement a robust acquisition, fully automated reconstruction, and processing pipeline using a novel rosette k-space pattern for UTE

methodsA multi-center feasibility/reproducibility study was conducted for the novel UTE

resultsThis novel acquisition and advanced processing techniques yielded high-quality spectra and enabled the detection of the critical brain metabolites at three different sites with different hardware specifications. In vivo, feasibility with an acceleration factor of 4 in 6.75 min resulted in a mean Cramér-Rao lower bounds below 20% for phosphocreatine (PCr), adenosine triphosphate (ATP), phosphomonoesters (PME), and a mean coefficient of variation for ATP/PCr below 20%.

conclusionWe demonstrated that UTE

Indexed as

BrainImaging, Three-DimensionalMagnetic Resonance ImagingAdultAlgorithmsFeasibility StudiesFemaleHumansImage Processing, Computer-AssistedMagnetic Resonance SpectroscopyMalePhosphorusReproducibility of ResultsPhosphorus3D 31P MRSIcompressed sensingrosette K‐space trajectory

Identifiers

PMID40692528
PMCPMC12501757

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.