Evidence map›Paper›PMID 40692579›Full record

ArticleFrontiers in neuroscience2025

Listening effort and stress in tinnitus: a multidimensional approach.

Giovanna Giliberto, Maria Itati Palacio, Giulia Cartocci, Emiliano Fernandez-Villalba, Dario Rossi, Nieves Minguez, Maria Botia, Jose Domingo Cubillana, Jose Joaquin Ceron, Fabio Babiloni and 1 more

Abstract read
In one paragraph

Article in Frontiers in neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Giovanna GilibertoClinical and Experimental Neuroscience (NiCE), Biomedical Research Institute of Murcia (IMIB-Pascual Parrilla), Institute for Aging Research, UniWell, Campus Mare Nostrum, School of Medicine, University of Murcia, Murcia, Spain.
Maria Itati PalacioClinical and Experimental Neuroscience (NiCE), Biomedical Research Institute of Murcia (IMIB-Pascual Parrilla), Institute for Aging Research, UniWell, Campus Mare Nostrum, School of Medicine, University of Murcia, Murcia, Spain.
Giulia CartocciDepartment of Molecular Medicine, University of Rome "Sapienza", Rome, Italy.
Emiliano Fernandez-VillalbaClinical and Experimental Neuroscience (NiCE), Biomedical Research Institute of Murcia (IMIB-Pascual Parrilla), Institute for Aging Research, UniWell, Campus Mare Nostrum, School of Medicine, University of Murcia, Murcia, Spain.
Dario RossiDepartment of Molecular Medicine, University of Rome "Sapienza", Rome, Italy.
Nieves MinguezDepartment of Otorhinolaryngologist, Virgen of Arrixaca University Clinical Hospital, Murcia, Spain.
Maria BotiaClinical and Experimental Neuroscience (NiCE), Biomedical Research Institute of Murcia (IMIB-Pascual Parrilla), Institute for Aging Research, UniWell, Campus Mare Nostrum, School of Medicine, University of Murcia, Murcia, Spain.
Jose Domingo CubillanaDepartment of Otorhinolaryngologist, Virgen of Arrixaca University Clinical Hospital, Murcia, Spain.
Jose Joaquin CeronClinical and Experimental Neuroscience (NiCE), Biomedical Research Institute of Murcia (IMIB-Pascual Parrilla), Institute for Aging Research, UniWell, Campus Mare Nostrum, School of Medicine, University of Murcia, Murcia, Spain.
Fabio BabiloniDepartment of Molecular Medicine, University of Rome "Sapienza", Rome, Italy.
Maria Trinidad HerreroClinical and Experimental Neuroscience (NiCE), Biomedical Research Institute of Murcia (IMIB-Pascual Parrilla), Institute for Aging Research, UniWell, Campus Mare Nostrum, School of Medicine, University of Murcia, Murcia, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This study investigated the impact of chronic tinnitus on auditory perception, text comprehension, and physiological stress responses, with a focus on sex-related differences. The main objectives were to assess the influence of sex and stress on tinnitus severity, examine neurophysiological indicators of listening effort, and evaluate the effects of background noise on perceived difficulty and listening pleasantness. Materials and methods: Forty-seven participants (24 with tinnitus, 23 controls) performed a listening task involving audiobook excerpts presented at different signal-to-noise ratios. Subjective ratings, comprehension scores, and physiological data were collected, including salivary alpha-amylase, electrodermal activity, heart rate, and EEG-based measures of listening pleasantness. Results: Control participants outperformed tinnitus participants during the initial quiet condition ( Discussion: These findings suggest that tinnitus imposes a measurable cognitive and emotional burden, influenced by both sex and stress responses. They emphasize the need for multimodal, personalized, and gender-sensitive approaches in the assessment and management of tinnitus.

Indexed as

auditory perceptionEEG analysisgender differencesstress biomarkerstinnitus

Identifiers

PMID40692579
PMCPMC12277253

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.