Evidence map›Paper›PMID 40693039›Full record

ArticleBiosafety and health2025

The prevalence and genetic characteristics of human bocavirus in patients with acute respiratory infection in China during 2012-2021.

Haoran Jiang, Baicheng Xia, Xujing Chi, Liwei Sun, Hongmei Xu, Wenhui Wang, Min Mu, Pengbo Yu, Xingyu Xiang, Feng Zhang and 7 more

Abstract read
In one paragraph

Article in Biosafety and health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Haoran JiangNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
Baicheng XiaNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
Xujing ChiNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
Liwei SunPrecision Medicine Research Center, Children's Hospital of Changchun, Changchun 130061, China.
Hongmei XuDepartment of Infectious Diseases, Children's Hospital Affiliated to Chongqing Medical University, Chongqing 400014, China.
Wenhui WangHenan Provincial Center for Disease Control and Prevention, Zhengzhou 450016, China.
Min MuSchool of Public Health, Anhui University of Science and Technology, Huainan 231131, China.
Pengbo YuInstitute of Viral Diseases Center for Disease Control and Prevention of Shaanxi Province, Xi'an 710054, China.
Xingyu XiangDepartment of Microbiology, Hunan Provincial Center for Disease Control and Prevention, Changsha 410005, China.
Feng ZhangLaboratory of Viral Diseases, Qingdao Municipal Centre for Disease Control and Prevention, Qingdao Institute of Prevention Medicine, Qingdao 266000, China.
Hui ZhangVirus Laboratory of Gansu Provincial Center for Disease Control and Prevention, Key Laboratory of Infectious Diseases of Gansu Province, Lanzhou 730050, China.
Caixiao JiangHebei Center for Disease Control and Prevention, Shijiazhuang 050021, China.
Linqing ZhaoLaboratory of Virology, Beijing Key Laboratory of Etiology of Viral Diseases in Children, Capital Institute of Pediatrics, Beijing 100020, China.
Zhenguo GaoInstitute for Infectious Disease Prevention and Treatment, Xinjiang Uygur Autonomous Region Center for Disease Control and Prevention, Urumqi 830002, China.
Kongxin HuInstitute of Health Inspection and Quarantine, Chinese Academy of Inspection and Quarantine, Beijing 100123, China.
Yan ZhangNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
Aili CuiNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human bocavirus (HBoV) is a common respiratory virus among patients with acute respiratory infection (ARI). To investigate the prevalence and genetic characteristics of HBoV, clinical specimens from 13,109 ARI patients were collected through active surveillance from 12 provinces of China during 2012-2021. Extracted nucleic acid was screened and the viral protein 1 (VP1) gene was directly amplified and sequenced in HBoV-positive specimens. 3.51 % of patients were HBoV-positive, with children under 5 years old accounting for 93.48 % of cases. HBoV detection rate increased from 2.35 % in 2012-2019 to 5.38 % in 2020 and 7.68 % in 2021, with a pronounced increase in children aged 2-4 years and in Southern China. The age group with the highest detection rate shifted from infants under 2 years in 2012-2019 to children aged 2-4 years in 2020-2021. The proportion of HBoV co-detections increased significantly in 2020-2021, from 43.98 % to over 60.00 %. All HBoV cases were identified as HBoV-1 with 165 full length sequences of VP1 gene obtained. No temporal or geographic clustering was observed. The VP1 gene evolved at a rate of 7.99 × 10

Indexed as

Acute respiratory infection (ARI)Genetic characteristicsHuman bocavirus (HBoV)Viral infection

Identifiers

PMID40693039
PMCPMC12276568

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.