ReviewCureus2025
Comparison of Ischemic Stroke Outcomes in Patients With and Without Metabolic Syndrome: A Systematic Review.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Lipocalin-2 deficiency attenuates kainic acid-induced hippocampal cell death in a high-fat diet-fed diabetic mice.Metabolic brain disease · 2026Article
- Ambient air and noise pollution effect on cardiovascular health risk and lifestyle intervention to attenuate it: study protocol for a randomized clinical trial.Frontiers in public health · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present systematic review aims to compare ischemic stroke outcomes in patients with and without metabolic syndrome. The Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guideline was followed during the conduct of this systematic review. The literature search encompassed extensive databases like PubMed, MEDLINE, ScienceDirect, and Cochrane Library. We included studies published between 2014 and 2024 in the English language that fulfilled inclusion and exclusion criteria. The quality of the included studies was assessed using appropriate tools tailored to the study design. The synthesis and analysis of data included a narrative summary of study characteristics, outcomes assessed, and main findings. The analyzed results demonstrate a multifaceted connection between metabolic syndrome and the outcomes of ischemic stroke. While several studies affirm that specific components of metabolic syndrome (MetS), notably hyperglycemia, hypertension, and waist circumference, are associated with increased risk and poor outcomes, the role of broader metabolic health appears nuanced. Some studies highlight that metabolic status (not solely weight or BMI) is paramount in predicting both acute events like early neurological deterioration (END) and recurrent strokes, suggesting tailored interventions focusing on metabolic health could enhance patient outcomes. This systematic review concluded that the risk of stroke and poor outcomes increased with the number of metabolic syndrome components like hypertension, elevated abdominal fat, and hyperglycemia.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.