Evidence map›Paper›PMID 40693095›Full record

ReviewCureus2025

The Management of Thyroid Eye Disease: From Current Practice to Future Perspectives.

Navnit Kaur Dhaliwal, Lubna Razzaq

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Navnit Kaur DhaliwalMedicine and Surgery, Queen Mary University of London, London, GBR.
Lubna RazzaqOpthalmology, Guy's and St. Thomas' NHS Foundation Trust, London, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid eye disease (TED) is a complex autoimmune disease, which can have debilitating and possibly sight-threatening consequences. TED can present with diplopia, strabismus, pain and exophthalmos. Despite pathophysiology not being fully elucidated, key components of the TED pathogenesis pathway have been established. Current management focuses on reducing inflammation in the active phase of TED and subsequently employs surgical interventions to rectify the clinical sequelae that arise post-inflammation. However, given the side effect profiles and varying efficacy of current treatment options, there is a need for newer advanced therapeutic options. Future therapies are focusing on biologic use and small-molecule antagonists. This could revolutionise the treatment of TED, as these therapeutic techniques target specific parts of the TED pathophysiological pathway unlike most of the current treatments available today. The current and future landscape of TED treatment is a rapidly changing scene. This article will provide an insight into the current therapeutic options for TED, whilst discussing future potential treatments.

Indexed as

endocrinology and diabetesgraves opthalmologyopthalmology ocular pathologythyroid eye disease (ted)thyroid peroxidase antibodies

Identifiers

PMID40693095
PMCPMC12278685

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.