Evidence map›Paper›PMID 40693384›Full record

ArticleJournal of feline medicine and surgery2025

Quantitative assessment of mucosal fibrosis and its correlation with disease severity and outcome in cats with chronic enteropathy.

Nicole Dausend, Evan J Cosgrove, Paula R Giaretta, Philip H Kass, Valerie Freiche, Sina Marsilio

Abstract read
In one paragraph

Article in Journal of feline medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nicole DausendSchool of Veterinary Medicine, University of California Davis, Davis, CA, USA.ORCID 0009-0001-2312-9590
Evan J CosgroveSchool of Veterinary Medicine, University of California Davis, Davis, CA, USA.
Paula R GiarettaSchool of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, TX, USA.ORCID 0000-0003-2261-281X
Philip H KassSchool of Veterinary Medicine, University of California Davis, Davis, CA, USA.ORCID 0000-0001-6213-0925
Valerie FreicheInternal Medicine Department, Ecole Nationale Vétérinaire d'Alfort, Maisons-Alfort, France.
Sina MarsilioSchool of Veterinary Medicine, University of California Davis, Davis, CA, USA.ORCID 0000-0002-0693-0669

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectivesThis study aimed to develop a quantitative scoring method for the evaluation of mucosal fibrosis (MF) and assess its correlation with World Small Animal Veterinary Association scores, clinical abnormalities, disease severity, diagnosis and outcome in cats with lymphoplasmacytic enteritis (LPE) or low-grade intestinal T-cell lymphoma (LGITL).MethodsFormalin-fixed, paraffin-embedded small intestinal biopsy specimens from 13 cats with LPE and 14 cats with LGITL were included. MF was quantitatively measured in three separate areas (villi, apical crypts [ACs] and basal crypts) using an image processing program. The fractional fibrotic area (%FFA) was calculated based on the mean fibrosis scores in five representative fields. MF was also scored by a single board-certified pathologist on sequential slides stained with either hematoxylin and eosin (H&E) or Masson's trichrome (MT) on a four-point scale in the areas described above. Statistical analysis was performed to assess the correlation between clinical and pathological variables, diagnosis and outcome.ResultsThe %FFA scores correlated well with fibrosis scores on MT stains (

Indexed as

Cat DiseasesEnteritisIntestinal MucosaAnimalsCatsChronic DiseaseFemaleFibrosisIntestine, SmallMaleSeverity of Illness IndexChronic enteropathyhistopathologylow-grade intestinal T-cell lymphomalymphoplasmacytic enteritismucosal fibrosis

Identifiers

PMID40693384
PMCPMC12290242

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.