Evidence map›Paper›PMID 40694259›Full record

ArticleEJNMMI research2025

Kinetics of the amino acid uptake tracer O-(2-[

Korbinian Krieger, Thomas Pyka, Clemens Mingels, Hasan Sari, Albert Gjedde, Axel Rominger, Paul Cumming

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJNMMI research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Functional pituitary adenoma imaging.Reviews in endocrine & metabolic disorders · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Korbinian KriegerDepartment of Nuclear Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Thomas PykaDepartment of Nuclear Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0000-0002-2686-2851
Clemens MingelsDepartment of Nuclear Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0000-0001-6761-5323
Hasan SariDepartment of Nuclear Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0000-0002-1504-1767
Albert GjeddeTranslational Neuropsychiatry Unit, Department of Clinical Medicine, Faculty of Health Sciences, Aarhus University, Aarhus, Denmark.ORCID https://orcid.org/0000-0002-3756-7401
Axel RomingerDepartment of Nuclear Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0000-0002-1954-736X
Paul CummingDepartment of Nuclear Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland. paul.k.cumming@gmail.com.ORCID http://orcid.org/0000-0002-0257-9621

Funding

Eidgenössische Technische Hochschule Zürich MedLab Fellowship 2023International Centers for Precision Oncology Foundation Research Grant
6 · The paper itself

Abstract

backgroundThe large neutral amino acid [

resultsThe analyses yielded estimates of regional unidirectional blood-brain clearance K

conclusionsCompartmental analysis results for [

Indexed as

[18F]Fluoroethoxy-L-tyrosine (FET)Blood brain barrierBrainLarge neutral amino acidsL-type amino acid transporterPhysiologicalPositron emission tomography (PET)

Identifiers

PMID40694259
PMCPMC12283531

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.