Evidence map›Paper›PMID 40694304›Full record

Trial reportApplied psychophysiology and biofeedback2025

Effectiveness of Mindfulness-Based Stress Reduction on Salivary Cortisol and α-amylase Level, Anxiety and Depression in Students: A Randomized and Parallel-Group Clinical Trial.

Saba Hassanvandi, Reza Mohammadzadegan, Seyed Hassan Saadat, Boshra Hatef, Shima Shahyad

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Applied psychophysiology and biofeedback, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Saba HassanvandiDepartment of Psychology and Counselling, Farhangian University, Rangoon Street, P.O. Box: 14665-889, Tehran, Iran.
Reza MohammadzadeganDepartment of Psychology, Khoy Branch, Islamic Azad University, Khoy, Iran.
Seyed Hassan SaadatNephrology and Uncology Research Center, Clinical Sciences Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Boshra HatefNeuroscience Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Shima ShahyadNeuroscience Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran. Shima.shahyad@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current trial aimed to assess the effectiveness of Mindfulness-Based Stress Reduction training on salivary cortisol and α-amylase levels, anxiety and depression of students. This research was an experimental trial with a pre-test-post-test design and a control group. The statistical population of the research included all students studying in the universities of Khoy, Iran in 2021. The sample consisted of 30 people who were assigned to two experimental and control groups equally. Stress, anxiety and depression scale (DASS-21), General Health Questionnaire (GHQ-28) and saliva samples were passively taken by ELISA laboratory method with special kits. Data analysis was done using an independent t-test and analysis of covariance using IBM-SPSS version 26 software. The results showed that MBSR training on general health, alpha-amylase level and alpha-amylase/cortisol ratio of experimental group participants was more effective than the control group (P < 0.05). However, it was not effective on students' cortisol levels (P > 0.05). According to the findings, it can be argued that MBSR training has been able to promote the psychological (DASS and general health) and hormonal (alpha amylase level and alpha-amylase/cortisol ratio) mental health indicators of the experimental group participants compared to the control group.

Indexed as

alpha-AmylasesAnxietyDepressionHydrocortisoneMindfulnessSalivary alpha-AmylasesStress, PsychologicalAdultFemaleHumansIranMaleSalivaStudentsYoung Adultalpha-AmylasesHydrocortisoneSalivary alpha-AmylasesCortisolMental healthMindfulness-based of stress reductionSalivary α-amylase

Identifiers

PMID40694304

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.