Evidence map›Paper›PMID 40696174›Full record

ArticleNature genetics2025

Genomics-driven discovery of superior alleles and genes for yellow rust resistance in wheat.

Jianhui Wu, Shengwei Ma, Jianqing Niu, Weihang Sun, Haitao Dong, Shusong Zheng, Jiwen Zhao, Shengjie Liu, Rui Yu, Ying Li and 14 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Article
  3. Unlocking the potential of spring wheat genetic resources: uncovering resistance sources against leaf rust and yellow rust.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Identification of stripe rust resistance loci in Gansu wheat landraces using genome-wide association analysis.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Article
  8. Genetic characteristics and agronomic traits in leafy head Chinese cabbage breeding.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Article
  9. Article
  10. Review
  11. Precise mapping of high-temperature adult-plant stripe rust resistance gene Yr52 in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Article
  12. Review
  13. Beyond Resistance Genes: Silencing Susceptibility.International journal of molecular sciences · 2026
    Review
  14. Article
  15. Unveiling the genetic architecture of stripe rust resistance in wheat: a region-specific GWAS in Xinjiang, China.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Article
  16. Article
  17. Review
  18. Review
  19. The pyramiding ofFrontiers in plant science · 2026
    Article
  20. Progress in Molecular Plant Science (2023-2025).Current issues in molecular biology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Jianhui Wu *State Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Agronomy, Northwest A&F University, Yangling, P. R. China. wujh@nwafu.edu.cn.ORCID http://orcid.org/0000-0001-8154-1199
Shengwei Ma *Yazhouwan National Laboratory, Sanya, P. R. China.ORCID http://orcid.org/0000-0001-6196-811X
Jianqing Niu *Yazhouwan National Laboratory, Sanya, P. R. China.ORCID http://orcid.org/0000-0002-1449-4318
Weihang Sun *State Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Agronomy, Northwest A&F University, Yangling, P. R. China.
Haitao Dong *State Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Agronomy, Northwest A&F University, Yangling, P. R. China.
Shusong Zheng *State Key Laboratory of Plant Cell and Chromosome Engineering, Institute of Genetics and Developmental Biology, Innovation Academy for Seed Design, Chinese Academy of Sciences, Beijing, P. R. China.
Jiwen ZhaoState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Agronomy, Northwest A&F University, Yangling, P. R. China.
Shengjie LiuState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Agronomy, Northwest A&F University, Yangling, P. R. China.
Rui YuState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Agronomy, Northwest A&F University, Yangling, P. R. China.
Ying LiState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Agronomy, Northwest A&F University, Yangling, P. R. China.
Jinyu HanState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Agronomy, Northwest A&F University, Yangling, P. R. China.
Yimin WangState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Agronomy, Northwest A&F University, Yangling, P. R. China.
Tiantian ChenState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Agronomy, Northwest A&F University, Yangling, P. R. China.
Chuanliang ZhangState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Agronomy, Northwest A&F University, Yangling, P. R. China.
Wenjing ZhangState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Agronomy, Northwest A&F University, Yangling, P. R. China.
Bingyou DingState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Agronomy, Northwest A&F University, Yangling, P. R. China.
Lu ChangState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Agronomy, Northwest A&F University, Yangling, P. R. China.
Wenbo XueState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Agronomy, Northwest A&F University, Yangling, P. R. China.
Weijun ZhengState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Agronomy, Northwest A&F University, Yangling, P. R. China.
Chunlian LiState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Agronomy, Northwest A&F University, Yangling, P. R. China.
Dejun HanState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Agronomy, Northwest A&F University, Yangling, P. R. China. handj@nwafu.edu.cn.ORCID http://orcid.org/0000-0002-4885-7359
Zhensheng KangState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Plant Protection, Northwest A&F University, Yangling, P. R. China. kangzs@nwafu.edu.cn.ORCID http://orcid.org/0000-0001-5575-0122
Qingdong ZengState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Plant Protection, Northwest A&F University, Yangling, P. R. China. zengqd@nwafu.edu.cn.ORCID http://orcid.org/0000-0002-7856-2340
Hong-Qing LingYazhouwan National Laboratory, Sanya, P. R. China. hqling@genetics.ac.cn.ORCID http://orcid.org/0000-0001-9988-2282

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Yellow rust (YR), caused by Puccinia striiformis f. sp. tritici, poses a significant threat to wheat production worldwide. Breeding resistant cultivars is crucial for managing this disease. However, our understanding of the genetic mechanisms underlying YR resistance remains fragmented. To address this, we conducted a comprehensive analysis with variome data from 2,191 wheat accessions worldwide and over 47,000 YR response records across several environments and pathogen races. Through genome-wide association studies, we established a landscape of 431 YR resistance loci, providing a rich resource for resistance gene deployment. Furthermore, we cloned genes corresponding to three resistance loci, namely Yr5x (effective against several P. striiformis f. sp. tritici races), Yr6/Pm5 (conferred resistance to two pathogen species) and YrKB (TaEDR2-B; conferring broad-spectrum rust resistance without yield penalty). These findings offer valuable insights into the genetic basis of YR resistance in wheat and lay the foundation for engineering wheat with durable disease resistance.

Indexed as

Disease ResistanceGenes, PlantPlant DiseasesTriticumAllelesBasidiomycotaGenome-Wide Association StudyGenomicsPlant BreedingPolymorphism, Single NucleotidePuccinia

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.