Evidence map›Paper›PMID 40697393›Full record

ArticleOphthalmology science

Retinal Vascular Fingerprints as Novel Biomarkers for Primary Angle Closure Disease Progression.

Jin Wang, Shumei Han, Dapeng Mou, Xin Tang, Danli Shi, Mingguang He, Chunyan Guo, Ningli Wang, Ye Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Ophthalmology science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jin WangBeijing Tongren Eye Center, Beijing Key Laboratory of Ophthalmology and, Visual Science, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Shumei HanNingxia Eye Hospital, People's Hospital of Ningxia Hui Autonomous Region, Yinchuan, China.
Dapeng MouBeijing Tongren Eye Center, Beijing Key Laboratory of Ophthalmology and, Visual Science, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Xin TangBeijing Tongren Eye Center, Beijing Key Laboratory of Ophthalmology and, Visual Science, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Danli ShiCentre for Eye and Vision Research (CEVR), The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, China.
Mingguang HeCentre for Eye and Vision Research (CEVR), The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, China.
Chunyan GuoLinfen Yaodu Eye Hospital, Linfen, Shanxi, China.
Ningli WangBeijing Tongren Eye Center, Beijing Key Laboratory of Ophthalmology and, Visual Science, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Ye ZhangBeijing Tongren Eye Center, Beijing Key Laboratory of Ophthalmology and, Visual Science, Beijing Tongren Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To evaluate retinal vascular parameters across primary angle-closure disease (PACD) stages and explore their association with glaucomatous optic neuropathy (GON). Design: A cross-sectional, hospital-based study. Participants: We enrolled 638 eyes from 425 participants aged ≥40 years with PACD and further classified them into primary angle closure suspect (PACS), primary angle closure (PAC), and primary angle closure glaucoma (PACG) groups. Methods: Retinal vascular parameters were measured using the Retinal-based Microvascular Health Assessment System and compared between 3 groups. A multivariable logistic mixed effects model was used to identify factors associated with the presence of GON. Main Outcome Measures: Vessel caliber, tortuosity, complexity, and branching angle parameters. Results: No significant differences in retinal vascular parameters were found between PACS and PAC groups. Eyes in PACG showed significant vascular changes compared to PACS ( Conclusions: Retinal "vascular geometric fingerprints" show significant alterations in eyes with PACG compared to PACS and are independently associated with the presence of GON. These findings offer new insights into the vascular changes in GON, and longitudinal studies are needed to determine their prognostic value and clinical utility in managing PACD. Financial Disclosures: The author(s) have no proprietary or commercial interest in any materials discussed in this article.

Indexed as

Glaucomatous optic neuropathyPrimary angle closure diseaseRetinal vascular fingerprints

Identifiers

PMID40697393
PMCPMC12281162

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.