ArticleRSC advances2025
Label-free biosensing of microRNA-423-5p in saliva sample of patients using KAUST catalysis center-1 modified dendritic AuNPs: a new platform towards early-stage diagnosis of oral cancer.
Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Electrochemical Biosensing Strategies for Oral Health: From Engineered Interfaces to Advanced Transistor Architectures.Advanced healthcare materials · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oral squamous cell carcinoma (OSCC) is the most prevalent form of oral cavity cancer and a leading cause of death globally with low survival rates. Early detection of OSCC is crucial for reducing morbidity and mortality. The microRNA-423-5p, a 23-nucleotide non-coding RNA, is a vital biomarker for accurate OC detection due to its high value in the Receiver Operating Characteristic (ROC) curve, ensuring selectivity for OC. A precise measurement of microRNA-423-5p in human biofluids facilitates accurate OC detection. This research introduces a novel electrochemical platform without the need for labeling, designed for the non-intrusive monitoring of microRNA-423-5p in human saliva samples using a DNA-based bioassay. In this approach, poly(β-cyclodextrin) was fabricated to serve as a biocompatible support on the glassy carbon electrode surface. Furthermore, KCC-1-nPr-NH-Arg, featuring a surface area of 104.9 m
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.