ArticleThe journal of allergy and clinical immunology. Global2025
Risk factors for asthma exacerbations.
Article in The journal of allergy and clinical immunology. Global, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02733016 (Seinäjoki Adult Asthma Study), which is not on this map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Seinäjoki Adult Asthma Study: A 12-year Real-life Follow-up Study of New-onset Asthma Diagnosed at Adult Age and Treated in Primary and Specialized Care. Finnish Title: Diagnoosista Hoitotasapainoon: Voidaanko Aikuisen Astman Hoitotasapainoa Ennustaa Diagnoosivaiheen löydösten ja Astman Ilmiasun Perusteella?
Who cites it
1 citing paper in PubMed.
- Association of general and central obesity with asthma attacks: A cross-sectional study based on NHANES 2021-2023.Pakistan journal of medical sciences · 2026Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The Global Initiative for Asthma (GINA) advises evaluation of risk factors for exacerbations. Patients with adult-onset asthma often have a problematic disease presentation with comorbidities. Not much information exists about the prevalence of exacerbation risk factors in adult-onset asthma patients. Objective: We evaluated the prevalence of exacerbation risk factors listed in the 2023 GINA Report and their association with exacerbations in patients with adult-onset asthma. Methods: In the Seinäjoki Adult Asthma Study, 203 patients with adult-onset asthma were followed for 12 years. Data were available for 17 of the 21 GINA risk factors. Exacerbation was defined as an unplanned health care visit with asthma exacerbation mentioned in the medical health records. ClinicalTrials.gov NCT02733016. Results: On average, patients had 3.8 asthma exacerbation risk factors, with poor adherence (54.7%), chronic rhinosinusitis (54.2%), and smoking (52.7%) being the most common. Four patients (2.0%) had no risk factors. Oral corticosteroid use and the number of exacerbations increased with the number of risk factors. Exacerbations were positively associated with gastroesophageal reflux disease (odds ratio [OR], 5.0; 95% confidence interval [CI], 1.7-15.1; Conclusions: Exacerbation risk factors are common in patients with adult-onset asthma, and the value of identifying a single risk factor may be low. Patients with multiple risk factors and/or gastroesophageal reflux disease should be emphasized in clinical practice.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.