Evidence map›Paper›PMID 40697974›Full record

ArticleBrain, behavior, & immunity - health2025

Sleep health associations with serum metabolites in healthy adults.

Charlotte Sørensen, Ilona Dudka, Ana Virel, Ingemar Kåreholt, Leonie Jt Balter, John Axelsson, Grégoria Kalpouzos, Shireen Sindi

Abstract read
In one paragraph

Article in Brain, behavior, & immunity - health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. A [Journal of neuroinflammation · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Charlotte SørensenDivision of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.
Ilona DudkaDepartment of Chemistry, Umeå University, Umeå, Sweden.
Ana VirelDepartment of Medical and Translational Biology, Umeå University, Umeå, Sweden.
Ingemar KåreholtDivision of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.
Leonie Jt BalterDepartment of Psychiatry, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands.
John AxelssonDepartment of Psychology, Stress Research Institute, Stockholm University, Stockholm, Sweden.
Grégoria KalpouzosAging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.
Shireen SindiDivision of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Study objectives: Short and long sleep duration as well as poor sleep quality have been linked to higher prevalence of metabolic disorders. However, it is still unclear how diverse sleep variables relate to different metabolic pathways. This study examines how different features of sleep health relate to serum metabolites. Methods: The study used data from 197 healthy individuals aged 20-79 (Females n = 103) from the IronAge study performed at Karolinska Institutet in Sweden. Sleep variables were assessed with the Karolinska Sleep Questionnaire, where the following variables were computed: sleep duration, sleep debt, midpoint, social jetlag (i.e., the discrepancy between midpoint on free and workdays), napping frequency and sleep quality. Morning fasting blood samples were collected and Results: Sleep duration, midpoint of sleep on free days, social jetlag and chronotype associated with eight metabolites at a significance level of Conclusion: These observations indicate that sleep timing features,

Indexed as

Karolinska sleep questionnaireMetabolomicsSleep healthSleep timing

Identifiers

PMID40697974
PMCPMC12281066

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.