Evidence map›Paper›PMID 40698008›Full record

ArticleJAC-antimicrobial resistance2025

Occurrence of cefotaxime-resistant and beta-lactamase-producing Enterobacterales in poultry from small-scale farms in the Copperbelt province of Zambia.

Situmbeko J Nasilele, Misheck Shawa, Harvey K Kamboyi, Bruno S J Phiri, Herman Chambaro, Tapiwa Lundu, Mike Nundwe, Angela Lungu, Ladslav Moonga, Masahiro Kajihara and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JAC-antimicrobial resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Situmbeko J NasileleBiomedical Sciences Department, School of Veterinary Medicine, University of Zambia, Lusaka 10101, Zambia.
Misheck ShawaHokudai Center for Zoonosis Control in Zambia, University of Zambia, Lusaka 10101, Zambia.
Harvey K KamboyiDivision of Infection and Immunity, International Institute for Zoonosis Control, Hokkaido University, N20 W10, Kita-ku, Sapporo 001-0020, Japan.
Bruno S J PhiriDepartment of Para-Clinical Studies, School of Veterinary Medicine, University of Zambia, Lusaka 10101, Zambia.
Herman ChambaroMinistry of Fisheries and Livestock, Central Veterinary Research Institute, Lusaka 10101, Zambia.
Tapiwa LunduBiomedical Sciences Department, School of Veterinary Medicine, University of Zambia, Lusaka 10101, Zambia.
Mike NundweInstitute of Basic and Biomedical Sciences, Levy Mwanawasa Medical University, Lusaka 10101, Zambia.
Angela LunguDepartment of Disease Control, School of Veterinary Medicine, University of Zambia, Lusaka 10101, Zambia.
Ladslav MoongaDivision of Infection and Immunity, International Institute for Zoonosis Control, Hokkaido University, N20 W10, Kita-ku, Sapporo 001-0020, Japan.
Masahiro KajiharaHokudai Center for Zoonosis Control in Zambia, University of Zambia, Lusaka 10101, Zambia.
Hirofumi SawaHokudai Center for Zoonosis Control in Zambia, University of Zambia, Lusaka 10101, Zambia.
Yasuhiko SuzukiDivision of Bioresources, International Institute for Zoonosis Control, Hokkaido University, Kita-ku, Sapporo, Japan.ORCID https://orcid.org/0000-0002-1313-1494
Hideaki HigashiDivision of Infection and Immunity, International Institute for Zoonosis Control, Hokkaido University, N20 W10, Kita-ku, Sapporo 001-0020, Japan.ORCID https://orcid.org/0000-0002-5370-7865
Amon SiameDepartment of Pathology and Microbiology, School of Medicine, University of Zambia, Lusaka 10101, Zambia.
Ntombi B MudendaDepartment of Clinical Studies, School of Veterinary Medicine, University of Zambia, Lusaka 10101, Zambia.
Mudenda B Hang'ombeDivision of Infection and Immunity, International Institute for Zoonosis Control, Hokkaido University, N20 W10, Kita-ku, Sapporo 001-0020, Japan.
Kaampwe MuzanduBiomedical Sciences Department, School of Veterinary Medicine, University of Zambia, Lusaka 10101, Zambia.ORCID https://orcid.org/0000-0002-8517-7272

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The inappropriate use of antimicrobials in poultry farming is associated with the emergence of antimicrobial-resistant Enterobacterales. This cross-sectional study aimed to identify various cefotaxime-resistant and β-lactamase-producing Enterobacterales and characterize their antimicrobial resistance profiles. Methods: Pooled cloacal and meat samples collected from market-ready broiler chickens in Kitwe and Ndola districts of Zambia were screened for cefotaxime-resistant Enterobacterales. The samples were inoculated on MacConkey agar supplemented with 1 mg/L cefotaxime. The cefotaxime-resistant isolates were further subjected to antimicrobial susceptibility tests. Further, the isolated cefotaxime-resistant Enterobacterales were analysed for Results: From a total of 114 pooled samples, 81 (71.1%) cefotaxime-resistant Gram-negative strains were isolated. These were dominated by Conclusions: The study revealed a high prevalence of cefotaxime-resistant Enterobacterales and multidrug resistance involving medically important antibiotics. Four

Identifiers

PMID40698008
PMCPMC12280279

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.