Trial reportSubstance use & addiction journal2026
The Association of Perceived Risk for Opioid Overdose and Subsequent Overdose Among a Cohort of Opioid Overdose Survivors Who Use Nonprescribed Opioids.
Trial report in Substance use & addiction journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
backgroundFatal opioid overdoses in the United States have rapidly increased since 1999. While several risk factors for overdose are known, the association of overdose risk perception with subsequent overdose is not well understood.
methodsWe used data from a randomized trial of a counseling intervention to reduce opioid overdose among overdose survivors who use nonprescribed opioids. Participants were followed up for 16 months with visits every 4 months. At study visits participants were asked how likely they were to overdose in the next 4 months (risk perception) and whether they had overdosed since their last visit. Responses of "extremely likely" or "likely" were considered "higher risk perception," and those of "neutral," "unlikely," and "extremely unlikely" were considered "lower risk perception." We conducted an adjusted generalized estimating equation among participants in the control group to examine the association of higher versus lower risk perception and subsequent overdose. We adjusted for visit, recent overdose, and sociodemographic characteristics that were selected
resultsAmong 135 control participants, median age was 42 years (interquartile range: 34-49) and over half were male (59%). Higher risk perception was associated with 2.65 times the adjusted odds of having a subsequent overdose compared with lower risk perception (95% confidence interval: 1.35-5.23,
conclusionsIncorporating an assessment of risk perception into opioid overdose prevention efforts may help prioritize prevention efforts.
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Registered trials
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