ArticleCerebral cortex (New York, N.Y. : 1991)2025
Whisker pad stimulation with different frequencies reveals non-uniform modulation of functional MRI signal across sensory systems in awake rats.
Article in Cerebral cortex (New York, N.Y. : 1991), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
- Brain-wide fMRI responses to auditory and visual stimuli in awake mice.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
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Abstract
Primary sensory systems are traditionally considered separate units, but emerging evidence highlights notable interactions between them. Using a quiet and motion-tolerant zero-echo time functional magnetic resonance imaging technique, we examined brain-wide cross-sensory responses to whisker pad stimulation in awake and anesthetized rats. Our results indicate that whisker pad stimulation activated not only the whisker-mediated tactile system, but also auditory, visual, high-order, and cerebellar regions, demonstrating brain-wide cross-sensory and associative activity. Based on response characteristics, non-core regions responded to stimulation in a markedly different way compared to the primary sensory system, likely reflecting distinct encoding modes among primary sensory, cross-sensory, and integrative processing. Lastly, while low-order sensory activity was detectable under anesthesia, high-order processing and the complex differences between primary, cross-sensory, and associative systems were evident only in the awake state. This study reveals novel aspects of the cross-sensory interplay of the whisker-mediated tactile system and underscores the challenges of observing these phenomena in anesthetized rats.
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