Evidence map›Paper›PMID 40699468›Full record

ReviewDiscover oncology2025

Advances in radiotherapy for mouth neoplasms: emerging technologies and future perspectives.

Xuhong Liu, Zhuoya Zhang, Xinyu Deng, Zekun Lang, Jianrong Wang

Abstract readReview
In one paragraph

Review in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xuhong Liu *Department of Oral Health, Gansu Provincial Maternity and Child-care Hospital, Gansu Provincial Central Hospital, Lanzhou, 730000, Gansu, China.
Zhuoya Zhang *The First Clinical Medical College of Lanzhou University, Lanzhou, 730000, Gansu, China.
Xinyu DengDepartment of Radiology, The Second Hospital of Dalian Medical University, Dalian, 116000, Liaoning, China.
Zekun LangThe First Clinical Medical College of Lanzhou University, Lanzhou, 730000, Gansu, China.
Jianrong WangDepartment of Oral Health, Gansu Provincial Maternity and Child-care Hospital, Gansu Provincial Central Hospital, Lanzhou, 730000, Gansu, China. 632060104@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral cancer is a common malignant tumor of the head and neck region, significantly impacting human health and quality of life. Radiotherapy has become an essential component of treatment, often used in combination with surgery and/or chemotherapy. Advances in radiotherapy techniques, such as intensity-modulated radiotherapy, image-guided radiotherapy, and proton beam therapy, have markedly improved clinical outcomes. Intensity-modulated radiotherapy, for example, has demonstrated 5-year overall survival rates ranging from 60 to 75%, with better local control and reduced toxicity compared to conventional radiotherapy. Proton therapy has shown promising results in sparing normal tissues and achieving high-dose conformity, leading to improved quality of life and comparable tumor control. This review highlights the recent technological developments, explores underlying molecular mechanisms and predictive biomarkers, and discusses future directions in the radiotherapeutic management of oral cancer, aiming to provide clinically valuable insights and evidence-based recommendations.

Indexed as

Carbon ion radiotherapyMouth neoplasmsRadiotherapy

Identifiers

PMID40699468
PMCPMC12287490

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.