Evidence map›Paper›PMID 40699716›Full record

ReviewCurrent issues in molecular biology2025

Applications of Growth Factors in Implant Dentistry.

Balen Hamid Qadir, Mohammed Aso Abdulghafor, Mohammed Khalid Mahmood, Faraedon Mostafa Zardawi, Mohammed Taib Fatih, Handren Ameer Kurda, Zana Fuad Noori, Herve Tassery, Delphine Tardivo, Arthur Falguiere and 2 more

Abstract readReview
In one paragraph

Review in Current issues in molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Balen Hamid QadirDepartment of Dentistry, Komar University of Science and Technology, Sulaimani 46001, Kurdistan, Iraq.
Mohammed Aso AbdulghaforCollege of Dentistry, Sulaymaniyah University, Sulaimani 46001, Kurdistan, Iraq.
Mohammed Khalid MahmoodFaculty of Medical and Paramedical Sciences, Aix-Marseille University, French National Center of Scientific Research (CNRS), French Blood Establishment (EFS), Bio-Cultural Anthropology, Law, Ethics and Health Laboratory (ADES), 13005 Marseille, France.ORCID 0000-0002-8093-9514
Faraedon Mostafa ZardawiDean of the Faculty of Dentistry, Qaiwan International University, Sulaimani 46001, Kurdistan, Iraq.ORCID 0000-0003-3650-3817
Mohammed Taib FatihDepartment of Dentistry, Komar University of Science and Technology, Sulaimani 46001, Kurdistan, Iraq.
Handren Ameer KurdaCollege of Dentistry, Sulaymaniyah University, Sulaimani 46001, Kurdistan, Iraq.
Zana Fuad NooriDepartment of Dentistry, American University of Sulaimani Iraq AUIS, Sulaimani 46001, Kurdistan, Iraq.
Herve TasseryDental School of Medicine, Conservative and Endodontic Department, Aix-Marseille University, 13005 Marseille, France.
Delphine TardivoFaculty of Medical and Paramedical Sciences, Aix-Marseille University, French National Center of Scientific Research (CNRS), French Blood Establishment (EFS), Bio-Cultural Anthropology, Law, Ethics and Health Laboratory (ADES), 13005 Marseille, France.
Arthur FalguiereOral Surgery Department, Timone University Hospital, 264 rue Saint Pierre, 13385 Marseille Cedex 5, France.
Vincent RomaoOral Surgery Department, Timone University Hospital, 264 rue Saint Pierre, 13385 Marseille Cedex 5, France.
Romain LanFaculty of Medical and Paramedical Sciences, Aix-Marseille University, French National Center of Scientific Research (CNRS), French Blood Establishment (EFS), Bio-Cultural Anthropology, Law, Ethics and Health Laboratory (ADES), 13005 Marseille, France.ORCID 0000-0002-5612-880X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Growth factors are proteins that play an essential part in tissue regeneration and development. They attach surface receptors to mediate their actions on cells. Signaling systems within cells are activated when growth factors bind to their associated receptors. These signaling cascades control the transcription of genes involved in cellular functions like proliferation, differentiation, migration, protein synthesis, and metabolism. This narrative review provides a comprehensive update on the use of growth factors in implant dentistry with a special emphasis on human clinical trials. Since wound healing and osseointegration are pre-requisites of successful implantation and growth factors are important components of homeostasis and wound healing, this review first starts with the basic biology of wound healing. Then, it presents the specific role of growth factors in wound healing and tissue regeneration. Finally, the PubMed database was searched using relevant keywords with some filters related to the research question. Out of the initial 44 records, all the clinical human studies (

Indexed as

concentrated growth factorsdental implantsgrowth factorsosseointegrationplatelet-derived growth factorsregenerative dentistrywound healing

Identifiers

PMID40699716
PMCPMC12110301

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.