ArticleAnnals of African medicine2026
Type 2 Diabetes in Morocco: Toward a Precision Diabetology, from Pathogenesis to Treatment.
Article in Annals of African medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundThe traditional classification of diabetes into types 1 and 2 does not reflect its heterogeneity in presentation, progression, treatment response, and complications.
methodsThis study explores a new classification based on five distinct subgroups to enhance understanding and management. Its applicability was tested in 1002 newly diagnosed Moroccan type 2 diabetes patients and compared with the Indian "WellGen" and Swedish "ANDIS" cohorts.
resultsNewly diagnosed Moroccan type 2 diabetics were mainly classified into four subgroups designated as: severe insulin deficiency diabetes (SIDD), severe insulin resistance diabetes (SIRD), mild obesity-related diabetes (MOD), and mild age-related diabetes (MARD). One thousand and two patients were included in our study with a sex ratio of 1. Patients were classified into the subgroups of MARD (42%), MOD (21%), and SIDD (19%), while SIRD was 14%. In our study, retinopathy and neuropathy were more prevalent in the SIDD subgroup, while nephropathy in the SIRD, while patients in the MARD group had a higher prevalence of cardiovascular complications.
conclusionsOur results provide useful clues as to the pathophysiological mechanisms and susceptibility to complications of type 2 diabetes in the Moroccan population, and suggest a need to review management strategies. Our results confirm the new diabetic subgroups proposed by similar studies, suggesting a possible generalization of this diabetes classification to Africa and the MENA region.
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