Evidence map›Paper›PMID 40700136›Full record

ArticleBiotech (Basel (Switzerland))2025

Monitoring of the Single-Cell Behavior of an

Prasika Arulrajah, Sophi Katharina Riessner, Anna-Lena Heins, Dirk Weuster-Botz

Abstract read
In one paragraph

Article in Biotech (Basel (Switzerland)), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Prasika ArulrajahChair of Biochemical Engineering, TUM School of Engineering and Design, Technical University of Munich, 85748 Garching, Germany.ORCID 0000-0002-0172-1454
Sophi Katharina RiessnerChair of Biochemical Engineering, TUM School of Engineering and Design, Technical University of Munich, 85748 Garching, Germany.
Anna-Lena HeinsInstitute of Bioprocess and Biosystems Engineering, Hamburg University of Technology, 21073 Hamburg, Germany.ORCID 0009-0007-2961-0848
Dirk Weuster-BotzChair of Biochemical Engineering, TUM School of Engineering and Design, Technical University of Munich, 85748 Garching, Germany.ORCID 0000-0002-1171-4194

Funding

Deutsche Forschungsgemeinschaft 8502/1-2
6 · The paper itself

Abstract

Large-scale bioprocesses often suffer from spatial heterogeneities, which impact microbial performance and often lead to phenotypic population heterogeneity. To better understand these effects at the single-cell level, this study applied, for the first time, automated real-time flow cytometry (ART-FCM) to monitor L-phenylalanine production with an

Indexed as

automated real-time flow cytometryEscherichia coli reporter strainfed-batchphenotypic population heterogeneityresidence timestirred-tank bioreactortwo-compartment bioreactor

Identifiers

PMID40700136
PMCPMC12285959

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.