Evidence map›Paper›PMID 40700389›Full record

ArticlePloS one2025

Repeatability of corneal measurements from the Casia2 anterior segment tomographer in a cataractous population.

Achim Langenbucher, Nóra Szentmáry, Alan Cayless, Daniel Schartmüller, Marcus Lisy, Rupert Menapace, Jascha Wendelstein, Christina Leydolt

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Achim LangenbucherDepartment of Experimental Ophthalmology, Saarland University, Homburg/Saar, Germany.ORCID https://orcid.org/0000-0001-9175-6177
Nóra SzentmáryDepartment of Experimental Ophthalmology, Saarland University, Homburg/Saar, Germany.
Alan CaylessSchool of Physical Sciences, The Open University, Milton Keynes, United Kingdom.ORCID https://orcid.org/0000-0003-0779-7449
Daniel SchartmüllerDepartment of Ophthalmology and Optometry, Vienna University Hospital, Vienna, Austria.
Marcus LisyDepartment of Ophthalmology and Optometry, Vienna University Hospital, Vienna, Austria.
Rupert MenapaceDepartment of Ophthalmology and Optometry, Vienna University Hospital, Vienna, Austria.
Jascha WendelsteinDepartment of Experimental Ophthalmology, Saarland University, Homburg/Saar, Germany.
Christina LeydoltDepartment of Ophthalmology and Optometry, Vienna University Hospital, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study was to investigate the repeatability of corneal power and thickness measures in a large patient cohort.

methodsIn this retrospective non-randomised cross sectional single-centre study we evaluated a dataset containing 900 Casia2 anterior segment tomography measurements from 300 eyes from 300 patients (3 repeat measurements each) taken prior to cataract surgery. Only complete measurements marked as 'Successful' and with a sequence of 3 measurements for each eye performed on the same day were considered. Keratometry (K), corneal back surface (P) and RealPower (R) were each decomposed into power vector components SEQ/C0/C45. The mean (MEAN) and standard deviations (SD) for each sequence of measurements were derived and analysed.

resultsFor K the MEAN and SD SEQ/C0/C45 were 43.77/0.17/-0.02 D and 0.12/0.18/0.18 D, for P MEAN and SD were -6.13/-0.25/0.00 D and 0.01/0.03/0.02 D, and for R MEAN and SD were 42.77/-0.06/-0.03 D and 0.13/0.19/0.19 D. For K and R 20%/42%/41% and 24%/45%/44% of repeat measurements respectively fell outside limits of ±1/8 D. The cornea was slightly thicker at the apex than at the thinnest point (544.6 vs. 536.2 µm) and SD was 4.3 vs. 3.9 µm. Keratometry underestimates against-the-rule corneal astigmatism by around 0.23 D.

conclusionsThe variation of corneal power with repeat measurements is in a range of ±1/8 D for keratometric and RealPower SEQ. Where the Casia2 is used for lens power calculation, repeat measurements could help to improve the refractive outcome.

Indexed as

Anterior Eye SegmentCataractCorneaTomographyAgedAged, 80 and overCataract ExtractionCross-Sectional StudiesFemaleHumansMaleMiddle AgedReproducibility of ResultsRetrospective Studies

Identifiers

PMID40700389
PMCPMC12286365

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.