Evidence map›Paper›PMID 40701574›Full record

ArticleRenal failure2025

Analysis of risk factors for perioperative hyperamylasemia in kidney transplant recipients.

Yang Zhang, Liubing Xia, You Luo, Jinhua Zhang, Zoufu Tang, Xiaorong Chen, Ning Na

Abstract read
In one paragraph

Article in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yang ZhangDepartment of Kidney Transplantation, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.ORCID 0000-0003-3418-0612
Liubing XiaDepartment of Kidney Transplantation, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.ORCID 0009-0000-9727-4427
You LuoDepartment of Kidney Transplantation, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Jinhua ZhangDepartment of Kidney Transplantation, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Zoufu TangDepartment of Kidney Transplantation, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Xiaorong ChenDepartment of Kidney Transplantation, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.ORCID 0000-0002-9902-8323
Ning NaDepartment of Kidney Transplantation, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPerioperative hyperamylasemia has been observed in several kidney transplant recipients (KTRs) at our center. However, there are currently no published reports on this observation. This study aimed to identify the risk factors associated with perioperative hyperamylasemia in KTRs.

methodsThe data from 540 deceased-donor kidney recipients in our hospital from January 2020 to December 2023 were retrospectively analyzed. Variables such as gender, past medical history, relevant laboratory tests, and trough concentration of calcineurin inhibitors (CNIs) at the time of serum amylase maximum were collected for all patients. Univariate and multivariate logistic regression analyses were used to determine the risk factors associated with perioperative hyperamylasemia.

resultsAmong all KTRs, 153 patients (28.3%) developed perioperative hyperamylasemia. Multivariate logistic regression analysis indicated that preoperative serum phosphate (odds ratio [OR] = 1.62, 95% confidence interval [CI]: 1.160 - 2.266,

conclusionElevated preoperative serum phosphate levels, preoperative serum amylase levels, and high perioperative CNIs trough concentrations are risk factors for perioperative hyperamylasemia. This study may provide valuable insights for clinicians to identify the causes of perioperative hyperamylasemia and formulate prevention and treatment strategies.

Indexed as

Calcineurin InhibitorsHyperamylasemiaKidney TransplantationPostoperative ComplicationsAdultAmylasesFemaleHumansLogistic ModelsMaleMiddle AgedPerioperative PeriodRetrospective StudiesRisk FactorsAmylasesCalcineurin Inhibitorscalcineurin inhibitorshyperamylasemiaperioperative hyperamylasemiaphosphateRenal transplantation

Identifiers

PMID40701574
PMCPMC12288184

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.