ReviewJournal of perinatology : official journal of the California Perinatal Association2025
Involving neonatal hematology and transfusion medicine in global efforts to eliminate severe retinopathy of prematurity.
Review in Journal of perinatology : official journal of the California Perinatal Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The oxygen paradox in retinopathy of prematurity: could fetal hemoglobin be the key?Frontiers in pediatrics · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Retinopathy of Prematurity (ROP) remains a worldwide problem. A more complete understanding of the pathogenesis might inform progress toward its elimination. ROP pathogenesis is undeniably complex, including preterm birth and oxygen exposure, but many other factors are implicated as well. In this Perspective, we focus on two pathogenic factors that are within the domain of neonatal hematology and transfusion medicine. Specifically, we address evidence that ROP pathogenesis can involve: 1) an elevated nucleated red blood cell (NRBC) count at preterm birth, as evidence of chronic hypoxia in utero, which should be recognized as a biomarker of elevated risk for developing ROP; and 2) transfusions of adult donor red blood cells (RBC) result in a dose-dependent elevation in adult hemoglobin (HbA), which can deliver and release excessive oxygen to the developing retina. Early studies indicate that eliminating adult donor RBC transfusions for vulnerable preterm infants might reduce or eliminate ROP.
Indexed as
Identifiers
40702158What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.