Evidence map›Paper›PMID 40702181›Full record

ArticleNature2025

Complete biosynthesis of salicylic acid from phenylalanine in plants.

Bao Zhu, Yanjun Zhang, Rong Gao, Zhihua Wu, Wei Zhang, Chao Zhang, Penghong Zhang, Can Ye, Linbo Yao, Ying Jin and 7 more

Abstract read
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Genome-Wide Identification of the PAL Gene Family inInternational journal of molecular sciences · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Towards an integrated molecular understanding of plant hormones.Journal of integrative plant biology · 2026
    Review
  15. Review
  16. Review
  17. How tobacco builds nicotine.Nature chemical biology · 2026
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Bao Zhu *Zhejiang Provincial Key Laboratory of Biotechnology on Specialty Economic Plants, College of Life Sciences, Zhejiang Normal University, Jinhua, China.ORCID 0009-0009-8939-1020
Yanjun Zhang *Zhejiang Provincial Key Laboratory of Biotechnology on Specialty Economic Plants, College of Life Sciences, Zhejiang Normal University, Jinhua, China. yjzhang@zjnu.cn.ORCID 0000-0002-7475-103X
Rong Gao *Zhejiang Provincial Key Laboratory of Biotechnology on Specialty Economic Plants, College of Life Sciences, Zhejiang Normal University, Jinhua, China.
Zhihua WuZhejiang Provincial Key Laboratory of Biotechnology on Specialty Economic Plants, College of Life Sciences, Zhejiang Normal University, Jinhua, China.ORCID 0000-0002-2895-7256
Wei ZhangZhejiang Provincial Key Laboratory of Biotechnology on Specialty Economic Plants, College of Life Sciences, Zhejiang Normal University, Jinhua, China.ORCID 0000-0001-8178-5433
Chao ZhangZhejiang Provincial Key Laboratory of Biotechnology on Specialty Economic Plants, College of Life Sciences, Zhejiang Normal University, Jinhua, China.
Penghong ZhangZhejiang Provincial Key Laboratory of Biotechnology on Specialty Economic Plants, College of Life Sciences, Zhejiang Normal University, Jinhua, China.
Can YeZhejiang Provincial Key Laboratory of Biotechnology on Specialty Economic Plants, College of Life Sciences, Zhejiang Normal University, Jinhua, China.
Linbo YaoZhejiang Provincial Key Laboratory of Biotechnology on Specialty Economic Plants, College of Life Sciences, Zhejiang Normal University, Jinhua, China.
Ying JinZhejiang Provincial Key Laboratory of Biotechnology on Specialty Economic Plants, College of Life Sciences, Zhejiang Normal University, Jinhua, China.
Hui MaoCollege of Chemistry and Materials Science, Zhejiang Normal University, Jinhua, China.
Peiyao TouZhejiang Provincial Key Laboratory of Biotechnology on Specialty Economic Plants, College of Life Sciences, Zhejiang Normal University, Jinhua, China.
Peng HuangZhejiang Provincial Key Laboratory of Biotechnology on Specialty Economic Plants, College of Life Sciences, Zhejiang Normal University, Jinhua, China.
Jiangzhe ZhaoZhejiang Provincial Key Laboratory of Biotechnology on Specialty Economic Plants, College of Life Sciences, Zhejiang Normal University, Jinhua, China.
Qiao ZhaoShenzhen Key Laboratory of Synthetic Genomics, Guangdong Provincial Key Laboratory of Synthetic Genomics, Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.ORCID 0000-0002-0958-4300
Chang-Jun LiuBiology Department, Brookhaven National Laboratory, Upton, NY, USA. cliu@bnl.gov.ORCID 0000-0001-6189-8756
Kewei ZhangZhejiang Provincial Key Laboratory of Biotechnology on Specialty Economic Plants, College of Life Sciences, Zhejiang Normal University, Jinhua, China. kwzhang@zjnu.edu.cn.ORCID 0000-0002-0844-1121

Funding

US Department of Energy, Office of Science, Office of Basic Energy Sciences
6 · The paper itself

Abstract

Salicylic acid (SA) is a pivotal phytohormone for plant responses to biotic and abiotic stresses. Plants have evolved two pathways to produce SA: the isochorismate synthase and phenylalanine ammonia lyase (PAL) pathways

Indexed as

OryzaPhenylalanineSalicylic AcidBiosynthetic PathwaysCinnamatesCoenzyme A LigasesCytochrome P-450 Enzyme SystemEvolution, MolecularIntramolecular TransferasesPeroxisomesPhenylalanine Ammonia-LyasePhylogenyPlant ProteinsCinnamatescinnamic acidCoenzyme A LigasesCytochrome P-450 Enzyme SystemIntramolecular Transferasesisochorismate synthasePhenylalaninePhenylalanine Ammonia-LyasePlant ProteinsSalicylic Acid

Identifiers

PMID40702181
PMCPMC12408352

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.