Evidence map›Paper›PMID 40702377›Full record

ArticleCell and tissue research2025

Functional role of circadian clock system in steroidogenesis and cell death pathways during corpus luteum regression in cattle.

Jing Zhang, Hanako Bai, Manabu Kawahara, Ahmed Z Balboula, Masashi Takahashi

Abstract read
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In one paragraph

Article in Cell and tissue research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jing ZhangGraduate School of Global Food Resources, Hokkaido University, Sapporo, Japan.
Hanako BaiResearch Faculty of Agriculture, Hokkaido University, Sapporo, Japan.
Manabu KawaharaResearch Faculty of Agriculture, Hokkaido University, Sapporo, Japan.
Ahmed Z BalboulaResearch Faculty of Agriculture, Hokkaido University, Sapporo, Japan.
Masashi TakahashiGraduate School of Global Food Resources, Hokkaido University, Sapporo, Japan. mmasashi@agr.hokudai.ac.jp.

Funding

Grant-in-Aid for Scientific Research from the Japan Society for the Promotion of Science (KAKENHI3) 22K1923
6 · The paper itself

Abstract

The corpus luteum (CL) is an ovarian structure that secretes progesterone (P4) following ovulation, playing a crucial role in regulating the estrous cycle and maintaining pregnancy. Luteolysis, the structural and functional degradation of the CL, occurs through apoptosis and autophagy. Recent studies suggest that the circadian clock (CC) system, particularly the gene NR1D1, is involved in these processes. This study investigated the role of NR1D1 in bovine CL regression using an ex vivo model treated with prostaglandin F

Indexed as

Circadian ClocksCorpus LuteumLuteolysisSteroidsAnimalsApoptosisCattleCell DeathDinoprostFemaleNuclear Receptor Subfamily 1, Group D, Member 1ProgesteroneDinoprostNuclear Receptor Subfamily 1, Group D, Member 1ProgesteroneSteroidsApoptosisAutophagyCircadian clock systemCorpus luteum regressionCow

Identifiers

PMID40702377

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.