ReviewInfectious agents and cancer2025
Molecular interaction of human papilloma virus (HPV) with microRANs: insights into the development of cervical cancer and treatment approaches.
Review in Infectious agents and cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- miR-4687-3p modulates cell proliferation and migration in cervical cancer cells.Molecular biology reports · 2026Article
- The role of the microbiome in gynecological cancers: implications for diagnosis and treatment.Frontiers in immunology · 2026Review
- The role of microRNAs on autophagy in cervical cancer: review.Discover oncology · 2025Review
- EGF induces SOD activity, TNF-α/IL-6 expression and complement regulatory proteins in cervical cancer cells: suppression by EGCG.Medical oncology (Northwood, London, England) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cervical cancer is one of the leading causes of cancer-related death among women worldwide, and high-risk human papillomavirus (HR-HPV) plays a crucial role in its development. HPV's oncogenic processes include the viral oncoproteins E6 and E7, which interfere with essential biological processes, causing DNA instability and uncontrolled cell growth. Recent research suggests that microRNAs (miRNAs) have a role in HPV-mediated tumor development, with dysregulation of particular miRNAs influencing cancer cell proliferation, immune escape, and therapy resistance. This review summarizes the most recent research on HPV's molecular interactions with host miRNAs, focusing on their functions in regulating tumor-suppressive genes and oncogenic mechanisms. Furthermore, we investigate HPV-induced epigenetic alterations that contribute to miRNA dysregulation and corresponding changes in cell cycle control, apoptosis, and metastasis. Discovering these molecular interactions provides fresh insights into personalized medicine techniques for CC detection and therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.