ArticleFrontiers in public health2025
Effectiveness of exercise in reducing symptom burden among hemodialysis patients: a non-pharmacological intervention approach.
Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07262879 (Effect of Nurse-Led Intradialytic Stretching Exercises on Muscle Cramp Burden Among Patients Undergoing Maintenance Hemodialysis), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Nurse-Led Intradialytic Stretching Exercises on Muscle Cramp Burden Among Patients Undergoing Maintenance Hemodialysis: A Randomized Controlled Trial
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effect of hemodialysis in end-stage renal disease patients on pulmonary function tests: a meta-analysis of cross-sectional studies.Frontiers in physiology · 2025Pooled it
- Muscle weakness, pain, and fatigue impair daily function in chronic kidney disease: a cross-sectional analysis from the I-RACE study.Renal failure · 2026Article
- Network-guided symptom targets in maintenance hemodialysis using in silico interventions: a multicenter cross-sectional study.BMC nephrology · 2026Observational
- Effect of nurse-led intradialytic stretching exercises on muscle cramp burden among patients undergoing maintenance hemodialysis: a randomized controlled trial.BMC nursing · 2026Article
- Perceptions of Exercise Benefits and Barriers and Physical Activity Status Among Patients Undergoing Hemodialysis in Saudi Arabia.Healthcare (Basel, Switzerland) · 2026Article
- Symptom Burden, Self-Efficacy, and Satisfaction with Nursing Care in Adults Undergoing Hemodialysis in Oman: A Cross-Sectional Study.Nursing reports (Pavia, Italy) · 2026Article
- Predictive utility of the multi-theory model in physical activity initiation and maintenance intentions among maintenance hemodialysis patients: a cross-sectional study.Frontiers in psychology · 2026Article
- Development of an Exercise Intervention Program During Dialysis for Patients on Maintenance Hemodialysis Based on the Health Belief Model.Journal of nursing management · 2026Article
- Evidence-based nursing strategies and quality of life in Saudi CKD patients with cardio-renal-metabolic comorbidities.BMC nursing · 2025Article
- Health-Related Quality of Life in Patients End-Stage Kidney Disease with Hypertension: Hemodialysis Vs Continuous Ambulatory Peritoneal Dialysis Using EQ-5D-5L at a Tertiary Center in Indonesia.International journal of nephrology and renovascular disease · 2025Article
Corrections and comments
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: End-stage renal disease (ESRD) patients undergoing hemodialysis (HD) often experience a substantial symptom burden, which negatively impacts their quality of life. While pharmacological treatments are commonly used to manage these symptoms, non-pharmacological interventions, such as exercise, have gained attention for their potential to alleviate both physical and psychological symptoms without additional medication-related side effects. Compared to other strategies that often target a limited range of symptoms-such as meditation for depression or music therapy for anxiety-exercise offers broader benefits, making it particularly promising for patients receiving HD. Objective: This study aimed to evaluate the effectiveness of an exercise intervention in reducing the symptom burden among patients receiving HD in Hail City, Saudi Arabia. Methods: A quasi-experimental pre-post intervention design was employed, involving (n = 72) HD patients recruited through convenience sampling from King Salman Specialist Hospital and King Khalid Hospital. Participants engaged in a structured exercise program for 12 weeks, with sessions conducted three times per week for 30 min. Symptom severity was assessed using the Dialysis Symptom Index (DSI) before and after the intervention. Data were analyzed using paired t-tests, with a significance level set at Results: A total of 72 HD patients participated in the study. The exercise intervention led to a statistically significant reduction in overall symptom severity scores, decreasing from 105.94 ± 9.77 pre-intervention to 102.50 ± 9.61 post-intervention ( Conclusion: The findings demonstrate that a structured exercise program is an effective non-pharmacological intervention for reducing symptom burden among HD patients. These results support incorporating exercise into routine HD care to enhance patient well-being. Future initiatives should focus on integrating supervised, accessible exercise programs into dialysis centers to maximize adherence and therapeutic benefit.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.