ArticleAlzheimer's & dementia (Amsterdam, Netherlands)
Underlying brain and genetic mechanisms linking historic phone use patterns, visual decline, and dementia risk in middle-aged and older adults.
Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Underlying brain and genetic mechanisms linking historic phone use patterns, visual decline, and dementia risk in middle-aged and older adults.Alzheimer's & dementia (Amsterdam, Netherlands)Article
Corrections and comments
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study aimed to investigate associations between historic phone use, visual decline, and risk of dementia, as well as underlying biological mechanisms.
methods
resultsOver a median follow-up of 12.2 years, participants with better visual acuity were associated with longer use of mobile phone. Longer historic phone use was associated with a 31% lower risk of dementia. Both hippocampal gray matter volumes and LTLs were associated with historic phone use length and significantly mediated the relationship between historic phone use and dementia. Mediation still exists in participants with visual decline.
conclusionOur findings suggest mobile phone use may serve as a modifiable factor to prevent dementia, even in older adults with visual decline. Highlights: A strong inverse association was observed between longer mobile phone use and lower dementia incidence, potentially mediated by changes in hippocampal gray matter volume and LTL.Mobile phone use may benefit individuals with age-related visual decline by reducing dementia risk, given the well-established link between vision impairment and increased dementia risk.Middle-aged and older adults should be encouraged to use mobile phones as a means to enhance social connectivity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.