Evidence map›Paper›PMID 40703448›Full record

ArticleiScience2025

Parabrachial

Fillan S Grady, Shantelle A Graff, McKenna M Warnock, Silvia Gasparini, Margaret M Tish, Yuxi Li, Gordon F Buchanan, Jon M Resch, Joel C Geerling

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Intersectional expression ofAmerican journal of physiology. Regulatory, integrative and comparative physiology · 2026
    Article
  3. Article
  4. AAV-PHP.eB Peripheral Delivery and Central Expression in Cre Mice.The Journal of comparative neurology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fillan S GradyDepartment of Neurology, University of Iowa, Iowa City, IA 52242, USA.
Shantelle A GraffDepartment of Neurology, University of Iowa, Iowa City, IA 52242, USA.
McKenna M WarnockDepartment of Neurology, University of Iowa, Iowa City, IA 52242, USA.
Silvia GaspariniDepartment of Neurology, University of Iowa, Iowa City, IA 52242, USA.
Margaret M TishDepartment of Neurology, University of Iowa, Iowa City, IA 52242, USA.
Yuxi LiDepartment of Neuroscience and Pharmacology, University of Iowa, Iowa City, IA 52242, USA.
Gordon F BuchananDepartment of Neurology, University of Iowa, Iowa City, IA 52242, USA.
Jon M ReschIowa Neuroscience Institute, University of Iowa, Iowa City, IA 52242, USA.
Joel C GeerlingDepartment of Neurology, University of Iowa, Iowa City, IA 52242, USA.

Funding

Brainstem cold-defense circuitryR01NS130038 · UNIVERSITY OF IOWA · 2025 to 2025
$525k
NINDS NIH HHS R01 NS130038
6 · The paper itself

Abstract

Cold environmental temperature is a threat to survival. Sustaining core body temperature in the cold requires a dynamic set of adaptive responses known as "cold defense," but the neural circuitry orchestrating these responses remains unclear. We identified a cluster of

Indexed as

Biological sciencesNatural sciencesNeurosciencePhysiologySensory neuroscienceSystems neuroscience

Identifiers

PMID40703448
PMCPMC12283563

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.