Evidence map›Paper›PMID 40703552›Full record

ReviewFrontiers in oncology2025

The impact of estrogen on benign breast tumors and exploration of recurrence mechanisms.

Zhe Fan, Huijin Wang, Yu Liu, Zongshuo Yu, Jingjing Li, Yuan Teng

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhe Fan *Department of Breast and Thyroid Surgery, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China.
Huijin Wang *Department of Breast and Thyroid Surgery, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China.
Yu LiuThyroid and Breast Surgery Department, The Third Affiliated Hospital of Sun Yat Sen University, Guangzhou, Guangdong, China.
Zongshuo YuSchool of Pediatrics, Guangzhou Medical University, Guangzhou, Guangdong, China.
Jingjing LiDepartment of Breast and Thyroid Surgery, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China.
Yuan TengDepartment of Breast and Thyroid Surgery, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Benign breast tumors are among the most common breast diseases affecting women, with their pathogenesis closely linked to hormonal influences, particularly estrogen. This review offers a comprehensive overview of the mechanisms through which estrogen affects benign breast tumors and examines the role of estrogen in tumor cell growth, proliferation, and apoptosis. Furthermore, this review explores the recurrence mechanisms of benign breast tumors, analyzing factors such as hormone dependence, microenvironmental influences, and genetic susceptibility. By generating relevant literature, this article aims to offer new insights into clinical treatment and prevention strategies aimed at managing benign breast tumors.

Indexed as

benign breast tumorsestrogenhormone dependencemicroenvironmentrecurrence mechanisms

Identifiers

PMID40703552
PMCPMC12283667

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.